Results 71 to 80 of about 16,684 (214)

Ensaio clínico randomizado para avaliação de dor e hematoma em administração de medicamentos por via subcutânea e intramuscular: há necessidade de troca de agulhas? [PDF]

, 2011
This clinical trial aimed at comparing the intensity of pain and bruising by subcutaneous and intramuscular injections using and retractable fixed syringes and needles and syringes with no needles combined, at a public hospital in São Paulo, for six ...
Ferreira, Barbara Carvalho, Lamblet, Luiz Carlos Ribeiro, Martucchi, Sergio Dias, Meira, Edilson Sant'Anna, Torres, Silvana   +4 more
core   +5 more sources

Update on innovative surgical techniques for omphalectomy in foals

Equine Veterinary Education, EarlyView.
Summary Umbilical infection is a common foal disorder, prone to complications, requiring surgical excision in severe cases. Timely surgical excision is the treatment of choice in these cases, as the infected umbilicus places the foal at risk for further fatal complications, such as sepsis and septic arthritis.
O. Haion, A. J. Tatz, R. Dahan, G. Kelmer   +3 more
wiley   +1 more source

Platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF): A systematic review across all fields of medicine

Periodontology 2000, EarlyView.
Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar, Mohammad Amin Amiri, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

Advancing Needle-Free Jet Injectors for Global Vaccine Delivery

Pharmaceutics
Background: Global immunization programs continue to rely on needle-based injections despite persistent concerns regarding sharps disposal, accidental injuries, and the technical skill required for accurate intradermal administration.
Peter Ikechukwu, Remigius Agu
doaj   +1 more source

Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum. [PDF]

, 2015
BackgroundA vaccine that interrupts malaria transmission (VIMT) would be a valuable tool for malaria control and elimination. One VIMT approach is to identify sexual erythrocytic and mosquito stage antigens of the malaria parasite that induce immune ...
Abebe, Yonas, Billingsley, Peter F, Eappen, Abraham G, Hoffman, Stephen L, Li, Minglin, Li, Tao, Padilla, Debbie, Richman, Adam M, Rodriguez-Barraquer, Isabel, Sim, B Kim Lee   +9 more
core   +1 more source

Technical note on an ovine model to study biomedical implants intended for maxillofacial reconstruction

Veterinary Surgery, EarlyView.
Abstract Objective To describe a repeated‐measures model permitting evaluation of up to four implants intended for maxillofacial applications in sheep. Animals Two‐year‐old Merino wethers (n = 5). Methods A retromandibular subparotid approach was developed through anatomical study of atlases, predissected models and cadaveric experiments.
Reza Sanaei, Ayda Farhoudi, Babatunde A. Ayodele, George Dimitroulis, Christina M. Murray, Helen M. Davies, Alastair J. Sloan, Charles N. Pagel   +7 more
wiley   +1 more source

Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine. [PDF]

PLoS ONE, 2017
Powder-injectors use gas propulsion to deposit lyophilised drug or vaccine particles in the epidermal and sub epidermal layers of the skin. We prepared dry-powder (Tg = 45.2 ± 0.5°C) microparticles (58.1 μm) of a MenY-CRM197 glyconjugate vaccine (0.5% wt.
Nikolas T Weissmueller, Leanne Marsay, Heiko A Schiffter, Robert C Carlisle, Christine S Rollier, Robert K Prud'homme, Andrew J Pollard   +6 more
doaj   +1 more source

Protection of mice against rotavirus challenge following intradermal DNA immunization by Biojector needle-free injection [PDF]

Vaccine, 2007
Mucosal administration (intranasal or oral) of a VP6 rotavirus vaccine to mice consistently elicits high levels of protection after rotavirus challenge (93->99% reductions in fecal rotavirus shedding) but only when co-administered with an effective adjuvant such as LT(R192G).
Anthony H-C, Choi, Kristi, Smiley, Mitali, Basu, Monica M, McNeal, Mingyuan, Shao, Judy A, Bean, John D, Clements, Richard R, Stout, Richard L, Ward   +8 more
openaire   +2 more sources

Geometry Analysis of Two Photon Polymerized Microneedles—An Experimental and Simulated Approach

Journal of Applied Polymer Science, Volume 143, Issue 22, June 10, 2026.
This research investigates the mechanical stability of hollow, two‐photon‐polymerized microneedles for drug delivery. In an experimental setup, a steel stamp gradually compresses 1000 μm‐tall microneedles while recording their force–deformation response.
Cordelia F. Wittemann, Selina Burkert, Christos J. Karapatzakis, Alexander Schwegler, Andreas Heinrich   +4 more
wiley   +1 more source

Intracellular Targeting of CEA Results in Th1-Type Antibody Responses Following Intradermal Genetic Vaccination by a Needle-Free Jet Injection Device

The Scientific World Journal, 2007
The route and method of immunization, as well as the cellular localization of the antigen, can influence the generation of an immune response. In general, intramuscular immunization results in Th1 responses, whereas intradermal delivery of DNA by gene ...
Susanne Johansson, Monica Ek, Britta Wahren, Richard Stout, Margaret A. Liu, Kristian Hallermalm   +5 more
doaj   +1 more source