Results 71 to 80 of about 10,233 (238)

Pancreatic Cystic Lesions: Pathogenesis and Malignant Potential

Diseases, 2018
Pancreatic cancer remains one of the most lethal cancers despite extensive research. Further understanding of precursor lesions may enhance the ability to treat and prevent pancreatic cancer.
Antoinette J. Pusateri, Somashekar G. Krishna   +1 more
doaj   +1 more source

Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao, Zhili Wang, Hyoyong Kim, Hui Kong, Junseok Lee, Jacqueline Ziqian Yang, Anmin Wang, Ryan Y. Zhang, Yong Ju, Jina Kim, Bing Feng, Dejun Liu, Yating Zhang, Zhenfang Wang, Yandong Zhang, Shujing Guo, Dekang Gao, James S. Tomlinson, Renjun Pei, Jipeng Wan, Stephen J. Pandol, Myung‐Shin Sim, Sungyong You, Ding Ma, Shaohua Lu, Na Sun, Hsian‐Rong Tseng, Yazhen Zhu   +27 more
wiley   +1 more source

Intraductal papillary mucinous neoplasm and the pancreatic incidentaloma

World Journal of Gastrointestinal Surgery, 2010
Asymptomatic pancreatic lesions (APL) are a commonly encountered problem in today's pancreatic surgical practices. Current literature regarding etiologies and incidence of APLs, particularly intraductal papillary mucinous neoplasm (IPMN), is presented.
Mark P. Callery, Charles M. Vollmer, Tara S. Kent   +2 more
openaire   +3 more sources

Main-duct intraductal papillary mucinous neoplasm of the pancreas: a case report

Clinical Management Issues, 2012
Three distinct entities among non-inflammatory cystic lesions of the pancreas have been defined: intraductal papillary mucinous neoplasm (IPMN), serous cystic neoplasm (SCN) and mucinous cystic neoplasm (MCN).
Natalia Manetti, Clara Faini, Francesca Bucciero, Giulia Razzolini, Maria Marsico, Maria Rosa Biagini, Stefano Milani   +6 more
doaj   +1 more source

Origin of Hypofunctional CD103+ NK Cells in Cirrhosis‐Associated Ascites

European Journal of Immunology, Volume 55, Issue 6, June 2025.
Ascites is one hallmark of decompensated liver cirrhosis. NK cells in cirrhosis‐associated ascites are a heterogeneous group of cells with altered functionality and CD103 expression identifies a subpopulation that is likely to be induced by cytokines present in the ascites fluid.
Christian Niehaus, Daniel Geanon, Ayesha Lietzau, Marija Jankovic, Christopher Maucourant, Benjamin Maasoumy, Ernesto Sparrelid, Heiner Wedemeyer, Julia Kahlhöfer, Christine S. Falk, Itzel Medina Andrade, Andrea Ponzetta, Niklas K. Björkström, Anke R.M. Kraft, Markus Cornberg, Benedikt Strunz   +15 more
wiley   +1 more source

Sarcopenia With High Subcutaneous Fat Predicts Metabolic Dysfunction Associated Steatotic Liver Disease Development After Pylorus Preserving Pancreaticoduodenectomy

World Journal of Surgery, Volume 49, Issue 6, Page 1611-1617, June 2025.
MASLD after PPPD affects not only the long‐term prognosis but also the availability of postoperative adjuvant chemotherapy, its prevention and treatment are important issues. The aim of this study is to analyze whether objective preoperative factors could predict the development of postoperative MASLD in patients after PPPD.
Masashi Nakagawa, Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toru Sano, Koichi Tomita, Masatoshi Shigoka, Satoshi Tabuchi, Eiji Hidaka, Shigeyuki Kawachi   +9 more
wiley   +1 more source

Emerging pathological diagnostic strategies for solid pseudopapillary neoplasm of the pancreas: insights from omics and innovative techniques

The Journal of Pathology: Clinical Research, Volume 11, Issue 3, May 2025.
Abstract Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare, low‐grade malignant tumor, representing 0.9–2.7% of all exocrine pancreatic tumors. SPN patients generally have a favorable prognosis with a 5‐year survival rate exceeding 95% following complete surgical resection.
Yuanhao Liu, Junya Peng, Yupei Zhao, Wenze Wang   +3 more
wiley   +1 more source

Ciliated Foregut Cyst of the Pancreas Presenting as a Mucinous Cystic Neoplasm

Journal of Digestive Endoscopy, 2018
A 53‑year‑old underwent an abdominal computed tomography for hematuria that incidentally discovered a cystic lesion of the pancreas. Endoscopic ultrasound revealed a structure with debris and septations; fine‑needle aspiration with negative cytology but ...
Nadia Huq, Wesley Papenfuss, Nalini M. Guda   +2 more
doaj   +1 more source

Comparative genomic analysis of the human gut microbiome reveals a broad distribution of metabolic pathways for the degradation of host-synthetized mucin glycans [PDF]

arXiv, 2017
The colonic mucus layer is a dynamic and complex structure formed by secreted and transmembrane mucins, which are high-molecular-weight and heavily glycosylated proteins. Colonic mucus consists of a loose outer layer and a dense epithelium-attached layer. The outer layer is inhabited by various representatives of the human gut microbiota (HGM). Glycans
arxiv  

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

Advanced Science, Volume 12, Issue 20, May 29, 2025.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng, Ge Hu, Shenbo Zhang, Rui Lv, Limeng Sun, Zhe Zhang, Zhengyu Jin, Yanyan Wu, Chen Huang, Lu Ye, Yunlu Feng, Zhe‐Sheng Chen, Zhiwei Wang, Huadan Xue, Aiming Yang   +14 more
wiley   +1 more source