Results 141 to 150 of about 38,020 (224)
Frontiers in OncologyCholangiocarcinoma is a malignancy known for its aggressiveness and limited treatment options. The malignant tumor behaviors include intrahepatic recurrence, regional lymph node (LN) metastasis, peritoneal carcinomatosis, and lung metastasis.
Heng-Jui Chang +3 more
doaj +1 more source
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
MedComm, Volume 7, Issue 2, February 2026.Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao +8 more
wiley +1 more source
Alterations of the oral microbiome in patients reinfected with SARS‐CoV‐2 omicron variants
VIEW, Volume 7, Issue 1, February 2026.We studied the oral microbiome (the community of microbes in the mouth) in people who were reinfected with the omicron variant of SARS‐CoV‐2 and compared it with healthy individuals and other respiratory illness groups. By sequencing tongue‐coating samples from large cohorts, we identified microbial shifts linked to Omicron reinfection and built a ...
Benchen Rao +17 more
wiley +1 more source
Cancer Science, Volume 117, Issue 2, Page 536-547, February 2026.Combined hepatocellular–cholangiocarcinoma (cHCC‐CCA) is a tumor consisting of a mixture of hepatocellular carcinoma and intrahepatic cholangiocarcinoma (CCA) components, but the mechanisms of development are poorly understood. The activation of Myc may be implicated in the formation of cHCC‐CCA and this work demonstrates for the first time that Myc ...
Masanori Goto +10 more
wiley +1 more source
Phase 2 study of combination SPI-1620 with docetaxel as second-line advanced biliary tract cancer treatment [PDF]
, 2017 A Rai +30 more
core +3 more sources
Cancer Science, Volume 117, Issue 2, Page 548-565, February 2026.This study indicates that SPP1, as an important regulator of tumor progression, is upregulated in various tumors and has been associated with a poor prognosis. SPP1+M2 has a unique spatial location at the forefront of tumor invasion and metastasis, thereby promoting tumor progression. MARCO+M2, which forms a mutually exclusive relationship with SPP1+M2,
Xuan Luo +15 more
wiley +1 more source
Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao +4 more
wiley +1 more source
Nature CommunicationsIntratumoral immune status influences tumor therapeutic response, but it remains largely unclear how the status determines therapies for patients with intrahepatic cholangiocarcinoma.
Jia-Cheng Lu +29 more
doaj +1 more source
Molecular Testing for Intrahepatic Cholangiocarcinoma: What, When, How? [PDF]
J Gastrointest CancerBarsch M +3 more
europepmc +1 more source