Results 51 to 60 of about 96,641 (177)
Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models
Pathology International, Volume 72, Issue 12, Page 589-605, December 2022., 2022 Abstract The biliary system is a highly branched tubular network consisting of intrahepatic bile ducts (IHBDs) and extrahepatic bile ducts (EHBDs). IHBDs are derived from hepatic progenitor cells, while EHBDs originate directly from the endoderm through a separate branching morphogenetic process.
Hiroyuki Tomita, Akira Hara
wiley +1 more source
Targeting Cholangiocarcinoma Cells By Cold Piezoelectric Plasmas: In Vitro Efficacy And Cellular Mechanisms [PDF]
Scientific Reports, Vol. 14, 30178, pp. 16 (2024)Cold piezoelectric plasma (CPP) is a novel approach in cancer therapy, enabling the development of portable treatment devices capable of triggering cancer cell death. While its effectiveness remains underexplored, this research focuses on its application against cholangiocarcinoma (CCA), an aggressive cancer of the biliary tract.
arxiv +1 more source
International Journal of Hyperthermia, 2020 Background & aims Very few data are available in literature about the role of radiofrequency ablation (RFA) in intrahepatic cholangiocarcinoma (ICC) and previous studies are mainly case reports and case series on a very small number of patients and ...
G. Brandi +13 more
semanticscholar +1 more source
BMC Cancer, 2021 Background Cholangiocarcinoma is a common malignant tumor of digestive system. LncRNA metallothionein 1 J, pseudogene (MT1JP) has been reported to play tumor-suppressing roles in multiple cancers.
Wei Zhao +5 more
semanticscholar +1 more source
Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology
ChemBioChem, EarlyView.This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda +2 more
wiley +1 more source
Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western Patients
JCO Precision Oncology, 2020 PURPOSE Intrahepatic cholangiocarcinoma (IHCCA), a global health problem, is increasing in incidence and has differing etiologies worldwide. Next-generation sequencing (NGS) is rapidly being incorporated into the clinical management of biliary cancers ...
Jingyu Cao +18 more
semanticscholar +1 more source
Neoadjuvant treatment strategies for intrahepatic cholangiocarcinoma
World Journal of Hepatology, 2020 Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver malignancy and is increasing in incidence. Long-term outcomes are optimized when patients undergo margin-negative resection followed by adjuvant chemotherapy.
C. Akateh, A. Ejaz, T. Pawlik, J. Cloyd
semanticscholar +1 more source
Towards Unsupervised Cancer Subtyping: Predicting Prognosis Using A Histologic Visual Dictionary [PDF]
arXiv, 2019 Unlike common cancers, such as those of the prostate and breast, tumor grading in rare cancers is difficult and largely undefined because of small sample sizes, the sheer volume of time needed to undertake on such a task, and the inherent difficulty of extracting human-observed patterns.
arxiv
Selecting Regions of Interest in Large Multi-Scale Images for Cancer Pathology [PDF]
arXiv, 2020 Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for computer vision algorithms to assist medical professionals in diagnosis of diseases ranging from malaria to cancer ...
arxiv
Cancer Discovery, 2019 ATP-competitive Fibroblast Growth Factor Receptor (FGFR) kinase inhibitors, including BGJ398 and Debio1347, show antitumor activity in patients with intrahepatic cholangiocarcinoma (ICC) harboring activating FGFR2 gene fusions.
L. Goyal +41 more
semanticscholar +1 more source