Results 71 to 80 of about 29,547 (250)

Feasibility of Comprehensive Genomic Profiling for Biliary Tract Cancer Using Transpapillary Biopsy Samples: A Prospective Study

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Graphical summary of the study design, intervention, and outcomes. ABSTRACT Background Patients with biliary tract cancer (BTC) often have actionable mutations, and comprehensive genomic profiling (CGP) plays an important role. However, the feasibility of CGP using transpapillary biopsy (TPB) samples remains unclear.
Kazuya Miyamoto   +9 more
wiley   +1 more source

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source

Cholangiocarcinoma in Backyard Chicken

open access: yesBrazilian Journal of Veterinary Pathology, 2013
Tumors arising from intrahepatic bile ducts and gall bladder have been described in several species of domestic animals. Cholangiocarcinoma is a neoplastic proliferation of the intrahepatic biliary system commonly reported in dogs, cats, sheep, cattle ...
Fernando Henrique da Silva Nóia   +6 more
doaj   +1 more source

Sarcomatoid intrahepatic cholangiocarcinoma in a patient with poor prognosis: a case report and literature review

open access: yesJournal of International Medical Research, 2020
Sarcomatoid intrahepatic cholangiocarcinoma (S-iCCA) is a rare histological variant of intrahepatic cholangiocarcinoma (iCCA). The diagnosis of S-iCCA is based on histopathological and immunohistochemical examinations, and S-iCCA often has a poorer ...
Xu Li   +4 more
doaj   +1 more source

Adenoma–carcinoma sequence in intrahepatic cholangiocarcinoma

open access: yes, 2012
IntroductionCholangiocarcinoma is a rare tumor but recent data report a worldwide increase in incidence and mortality. There are several risk factors associated with cholangiocarcinoma, and chronic inflammation of billiary tree seems to be implied in the
Oliveira, Manuel   +6 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

Case Report of Concomitant Diagnosis of Locally Advanced Intrahepatic Cholangiocarcinoma and Solitary Plasmacytoma of T11 Vertebra: Impact on Diagnostic and Clinical Management

open access: yesCurrent Oncology
A solitary bone plasmacytoma is a rare tumor. Intrahepatic cholangiocarcinoma is the second most common primary liver cancer after hepatocellular carcinoma.
Yann Touchefeu   +6 more
doaj   +1 more source

Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma [PDF]

open access: yes, 2014
Intrahepatic cholangiocarcinoma is a treatment refractory malignancy with a high mortality and an increasing incidence worldwide. Recent studies have observed that activation of Notch and AKT signaling within mature hepatocytes is able to induce the ...
Sansom, Owen J   +11 more
core   +1 more source

TGF-β1 expression is associated with invasion and metastasis of intrahepatic cholangiocarcinoma

open access: yesBiological Research, 2015
BACKGROUND: Transforming growth factor (TGF)-β is involved in many physiologic processes, it often promotes metastasis, and its high expression is correlated with poor prognosis.
Yijie Chen   +5 more
doaj   +1 more source

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