Results 91 to 100 of about 29,547 (250)
Artificial Organs, EarlyView.Extracorporeal albumin dialysis (OPAL) effectively reduces bilirubin and improves other laboratory markers in posthepatectomy liver failure, particularly in secondary forms. It may serve as a bridging therapy to support hepatic recovery in critically ill patients, although prospective studies are needed to confirm its impact on survival.
Dorian Marckmann +16 more
wiley +1 more source
, 2019 Background: Tumor burden is an important factor in defining prognosis among patients with primary and secondary liver cancers. Although the eighth edition of the American Joint Committee on Cancer staging system has changed the criteria for staging ...
Maithel, Shishir K +36 more
core +2 more sources
Cancer Science, EarlyView.Through bioinformatic analyses, iCCA cell models, and in vivo xenograft experiments, we show that autophagy inhibition sensitizes iCCA to MEK1/2 blockade by enhancing STING‐dependent type I interferon signaling. These findings support combined MEK1/2 and autophagy inhibition as a promising therapeutic strategy for iCCA. ABSTRACT The RAF–MEK–ERK pathway
Chengqiang Sun +15 more
wiley +1 more source
, 2015 aAPC = annual percent change.bAAPC = average annual percent change.*Significant at ...
Zaria Tatalovich (716644) +6 more
core +1 more source
Cancer Science, EarlyView.Bile‐derived exosomal miR‐196a and miR‐196b are identified as novel biomarkers for biliary tract cancer. Serum miR‐196a levels are significantly elevated in advanced disease with metastasis, while both miRNAs contribute to tumor progression by promoting cancer cell proliferation and invasion.
Naotaka Kugiyama +20 more
wiley +1 more source
Factors of Early Recurrence After Resection for Intrahepatic Cholangiocarcinoma
, 2022 International audienceBackgroundTwo‐thirds of patients undergoing liver resection for intrahepatic cholangiocarcinoma experience recurrence after surgery.
Hobeika, Christian +11 more
core +1 more source
GEVIS: A Workflow‐Driven Visual Analytics Approach to Differential Gene Expression Analysis
Computer Graphics Forum, EarlyView.Abstract Differential gene expression (DGE) analysis is one of the most widely used techniques for investigating RNA‐seq data and supports numerous medical and biological applications, including biomarker identification for diagnosis and prognosis, as well as the evaluation of medical treatments.
G. Blasilli +4 more
wiley +1 more source
Detection of Lymph Node Metastasis Using PET/CT in Cholangiocarcinoma
, 2007 We herein describe a 71-year-old female case of cholangiocarcinoma. Computed tomography of the abdomen showed an infiltrating lesion with low attenuation and a dilatation of the intrahepatic bile duct in the lateral segment of the liver.
Minami, Shigeki +4 more
core
Cell Proliferation, EarlyView.Song et al. developed an mGM‐CSF‐loaded, liver cancer cell‐based vaccine that potently activated dendritic cells and elicited tumour‐specific T cell responses. Mechanistically, radiation‐induced oxidative damage to mitochondrial DNA in cancer cells triggers the cGAS‐STING pathway in DCs, which synergizes with mGM‐CSF‐driven JAK2‐STAT3 signalling to ...
Zhiruo Song +15 more
wiley +1 more source
Intrahepatic cholangiocarcinoma in a transplant liver - selective internal radiation therapy followed by right hemihepatectomy: report of a case [PDF]
, 2014 Intra- or extrahepatic cholangiocarcinomas are the second most common primary liver malignancies behind hepatocellular carcinoma. Whereas the incidence for intrahepatic cholangiocarcinoma is rising, the occurrence of extrahepatic cholangiocarcinoma is ...
Sperling, Jens +11 more
core +1 more source