Results 81 to 90 of about 29,547 (250)

Surgical Aspects of Intrahepatic Cholangiocarcinoma

, 2022
Intrahepatic cholangiocarcinoma (ICC) is a rare and aggressive malignancy. It originates from the bile ducts and is the second most common primary cancer of the liver. Surgery is considered the only curative treatment of ICC, offering the best chance for
Arie Ariche, Kupietzky, Amram, Amram Kupietzky, Ariche, Arie   +3 more
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Heterochronous Adrenal Metastasis from Intrahepatic Cholangiocarcinoma: Report of a Case

, 2014
We herein report a case of laparoscopic adrenalectomy for solitary adrenal metastasis from intrahepatic cholangiocarcinoma (ICC). Although the treatment of extrahepatic metastasis from primary liver tumors is essentially palliative, solitary metastasis ...
Adachi, Tomohiko, Maruya, Yasuhiro, Okamoto, Tatsuya, Kuroki, Tamotsu, Abe, Kuniko, Kanematsu, Takashi, Eguchi, Susumu   +6 more
core  

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Prognostic impact of RPL15 overexpression in intrahepatic cholangiocarcinoma: a marker of aggressive tumor behavior

Diagnostic Pathology
Background Overexpression of ribosomal proteins has been found in several cancer types and has an important role in cell proliferation and tumorigenesis. Analysis of the expression profiles of cholangiocarcinoma revealed that ribosomal protein L15 (RPL15)
Wen-Ching Wang, Chien-Jui Huang, Han-Ping Hsu, Yu-Hsuan Kuo, Khaa Hoo Ong, Ding-Ping Sun, Yu-Feng Tian, Chia-Ling Chou, Ti-Chun Chan, Chung-Hsi Hsing, Wan-Shan Li, Hong-Lin He   +11 more
doaj   +1 more source

A novel nomogram for the prediction of intrahepatic cholangiocarcinoma in patients with intrahepatic lithiasis complicated by imagiologically diagnosed mass

, 2018
Gang Chen,1 Huajun Yu,1 Yi Wang,2 Chenhao Li,2 Mengtao Zhou,1 Zhengping Yu,1 Xiangwu Zheng,3 Xiuling Wu,4 Yunfeng Shan,1 Qiyu Zhang,1 Qiqiang Zeng1 1Department of Hepatobiliary Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou ...
Zhou M, Shan Y, Zheng X, Zeng Q, Li C, Chen G, Wang Y, Yu Z, Yu H, Zhang Q, Wu X   +10 more
core  

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source

Metallothionein overexpression and its prognostic relevance in intrahepatic cholangiocarcinoma and extrahepatic hilar cholangiocarcinoma (Klatskin tumors)

, 2009
Metallothionein is a group of small molecular weight cysteine-rich proteins with a broad variety of functions. Metallothionein has been shown to regulate apoptosis and proliferation. Overexpression of metallothionein frequently occurs in human tumors and
Baba, Hideo Andreas, Schmitz, Klaus Jūrgen, Schmid, Kurt Werner, Kaiser, Gernot, Jasani, Bharat, Sotiropoulos, Georgios Charalambos, Lang, Hauke, Wohlschlaeger, Jeremias   +7 more
core   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Hepatitis B virus and intrahepatic cholangiocarcinoma

, 2007
Intrahepatic cholangiocarcinoma (ICC) is a rare type of primary liver cancer that arises from intrahepatic bile ducts. Its etiopathogenesis has been considered to be independent of the presence of chronic viral hepatitis infections or cirrhosis.
Vasiou, K., Dalekos, G. N., Tepetes, K., Loukopoulos, A., Gatselis, N. K., Gioti, C., Zafiriou, A.   +6 more
core   +1 more source