Results 81 to 90 of about 38,020 (224)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Pathology of intrahepatic cholangiocarcinoma [PDF]

HepatoBiliary Surgery and Nutrition, 2017
Intrahepatic cholangiocarcinoma (iCC) is a primary carcinoma of the liver with increasing significance and major pathogenic, clinical and therapeutic challenges. Classically, it arises from malignant transformation of cholangiocytes bordering small portal bile duct (BD) to second-order segmental large BDs. It has three major macroscopic growth pattern [
Vijgen, Sandrine Elisabeth V, Terris, Benoit, Rubbia-Brandt, Laura   +2 more
openaire   +3 more sources

Minute nodular intrahepatic cholangiocarcinoma [PDF]

Cancer, 1998
This study describes the clinicopathologic features of minute intrahepatic cholangiocarcinoma (ICC) and clarifies the relation between minute nodular ICC and hepatitis viral infection.The presence of hepatitis C virus antibody (anti-HCV) and hepatitis B surface antigen (HBsAg) was examined in the serum of 50 patients with ICC who underwent hepatectomy ...
M, Yamamoto, K, Takasaki, M, Nakano, A, Saito   +3 more
openaire   +2 more sources

Staging of intrahepatic cholangiocarcinoma [PDF]

HepatoBiliary Surgery and Nutrition, 2017
Intrahepatic cholangiocarcinoma (ICC) comprises approximately 5-30% of primary liver tumors, however it has been increasing over the last several decades. Up to and including the 6th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) edition staging system, ICC was staged the same as hepatocellular ...
Sean M, Ronnekleiv-Kelly, Timothy M, Pawlik   +1 more
openaire   +2 more sources

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

iMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui, Jiameng Li, Caifeng Li, Mo Sun, Wei Liu, Xuxia Cao, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen   +9 more
wiley   +1 more source

TGF-β1 expression is associated with invasion and metastasis of intrahepatic cholangiocarcinoma

Biological Research, 2015
BACKGROUND: Transforming growth factor (TGF)-β is involved in many physiologic processes, it often promotes metastasis, and its high expression is correlated with poor prognosis.
Yijie Chen, Lin Ma, Qian He, Shaobo Zhang, Chenghua Zhang, Wei Jia   +5 more
doaj   +1 more source

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou, Alvarez, Block, Boonstra, Deneau, Dotson, Faubion, Feldstein, Goyal, Gregorio, Halliday, Hirschfield, Hov, Jose, Jose, Levine, Levine, Liberal, Loftus, Loftus, Lundqvist, Maggiore, Malaty, Mieli-Vergani, Navaneethan, Noble-Jamieson, Olsson, Ordonez, Penna, Rönnblom, Sokol, Zholudev   +31 more
core   +1 more source

Neoadjuvant Chemotherapy With Gemcitabine/Cisplatin/S‐1 for Resectable Biliary Tract Cancer With FDG‐PET‐Positive Lymph Node Metastasis (KHBO1201): A Multicenter Phase II Trial

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Purpose To evaluate the safety and efficacy of neoadjuvant gemcitabine, cisplatin, and S‐1 (GCS) chemotherapy for resectable biliary tract cancer (BTC) and FDG‐PET‐positive lymph nodes in a multicenter phase II study (KHBO1201). Methods Patients with resectable BTC (intrahepatic/extrahepatic bile duct, gallbladder, or ampullary cancers) and ...
Satoshi Ogiso, Etsuro Hatano, Satoru Seo, Masashi Kanai, Shogo Kobayashi, Hiroshi Wada, Hidetoshi Eguchi, Tatsuya Higashi, Hiroaki Nagano, Tatsuya Ioka   +9 more
wiley   +1 more source

Case Report of Concomitant Diagnosis of Locally Advanced Intrahepatic Cholangiocarcinoma and Solitary Plasmacytoma of T11 Vertebra: Impact on Diagnostic and Clinical Management

Current Oncology
A solitary bone plasmacytoma is a rare tumor. Intrahepatic cholangiocarcinoma is the second most common primary liver cancer after hepatocellular carcinoma.
Yann Touchefeu, Matthieu Barbaud, Laura Prin-Felix, Edouard Samarut, Bastien Jamet, Luc Ollivier, Damien Bouda   +6 more
doaj   +1 more source

Intrahepatic Sarcomatous Cholangiocarcinoma: Case Report and Review of the Literature

Case Reports in Surgery, 2018
The authors report a case of a patient with intrahepatic sarcomatous cholangiocarcinoma. A 45-year-old Thai man presented with a 3-month history of right upper abdominal pain.
Thana Boonsinsukh, Vichit Viriyaroj, Thammanij Rookkachart, Therdkiat Trongwongsa   +3 more
doaj   +1 more source