Muscle Conditional Medium Reduces Intramuscular Adipocyte Differentiation and Lipid Accumulation through Regulating Insulin Signaling. [PDF]
Due to the paracrine effects of skeletal muscle, the lipid metabolism of porcine intramuscular (i.m.) preadipocytes was different from that of subcutaneous (s.c.) preadipocytes. To investigate the development of i.m. preadipocytes in vivo, the s.c. preadipocytes were cultured with muscle conditional cultured medium (MCM) for approximating extracellular
Han H +6 more
europepmc +6 more sources
Muscle-specific downregulation of GR levels inhibits adipogenesis in porcine intramuscular adipocyte tissue. [PDF]
AbstractIntramuscular adipose is conducive to good pork quality, whereas subcutaneous adipose is considered as waste in pig production. So uncovering the regulation differences between these two adiposes is helpful to tissue-specific control of fat deposition.
Chu W +8 more
europepmc +6 more sources
miR-128-3p inhibits intramuscular adipocytes differentiation in chickens by downregulating FDPS
Background Intramuscular fat (IMF) content is the major indicator for evaluating chicken meat quality due to its positive correlation with tenderness, juiciness, and flavor.
Shuaipeng Zhu +17 more
doaj +3 more sources
FOS Inhibits the Differentiation of Intramuscular Adipocytes in Goats [PDF]
Goat intramuscular fat (IMF) deposition is precisely regulated by many key genes as well as transcription factors. Nevertheless, the potential of the regulators of goat IMF deposition remains undefined. In this work, we reported that the transcription factor FOS is expressed at a low level at the early differentiation stage and at a high level in late ...
Tingting Hu +10 more
openalex +3 more sources
Adipogenesis involves complex interactions between transcription and metabolic signalling. Exploration of the developmental characteristics of intramuscular adipocyte will provide targets for enhancing beef cattle marbling without increasing obesity. Few
Xiaoyu Wang +13 more
doaj +3 more sources
Integrated analysis of lactylation modification and proteomics revealed potential epigenetic regulation in intramuscular fat deposition of Xidu black pigs [PDF]
Background Pork serves as a significant meat commodity, with intramuscular fat (IMF) content being a critical determinant of its quality. However, the epigenetic mechanism of porcine IMF deposition is still unclear.
Tong Chen +11 more
doaj +2 more sources
gga-miRNA-18b-3p Inhibits Intramuscular Adipocytes Differentiation in Chicken by Targeting the ACOT13 Gene [PDF]
Intramuscular fat (IMF) is the most important evaluating indicator of chicken meat quality, the content of which is positively correlated with tenderness, flavor, and succulence of the meat.
Guirong Sun +11 more
doaj +3 more sources
Bovine Adipocyte-Derived Exosomes Transport LncRNAs to Regulate Adipogenic Transdifferentiation of Bovine Muscle Satellite Cells [PDF]
Intramuscular fat content is a key factor in determining the quality and value of beef. Intramuscular adipocytes and satellite cells can interact with each other, and both are the source cells for intramuscular fat formation.
Guangyao Meng +8 more
doaj +2 more sources
PLIN5 Promotes Lipid Reconstitution in Goat Intramuscular Fat via the PPARγ Signaling Pathway [PDF]
Intramuscular fat (IMF) content is an important factor of goat meat quality, which is related to the proliferation and differentiation of intramuscular preadipocytes.
Yuhan Dai +10 more
doaj +2 more sources
Ruminant fat is often perceived as having a negative impact on human health; however, the composition of the fat is under complex biochemical control and can be improved through strategic manipulation of the animal’s diet. There were two major objectives
S.M. Waters +6 more
doaj +2 more sources

