AQP3 Facilitates Proliferation and Adipogenic Differentiation of Porcine Intramuscular Adipocytes [PDF]
Genes, 2020 The meat quality of animal products is closely related to the intramuscular fat content. Aquaglyceroporin (AQP) defines a class of water/glycerol channels that primarily facilitate the passive transport of glycerol and water across biological membranes.
Xiaoyu Wang +5 more
openaire +2 more sources
miR-34a regulates adipogenesis in porcine intramuscular adipocytes by targeting ACSL4 [PDF]
BMC Genetics, 2020 AbstractBackgroundIntramuscular fat (IMF) content is an important factor in porcine meat quality. Previously, we showed that miR-34a was less abundant in liver tissue from pigs with higher backfat thickness, compared to pigs with lower backfat thickness.
Wenwen Wang +6 more
openaire +3 more sources
Chromium Propionate Enhances Adipogenic Differentiation of Bovine Intramuscular Adipocytes [PDF]
Frontiers in Veterinary Science, 2015 In vitro experiments were performed to determine the effects of increasing concentrations of chromium propionate (CrPro) on mRNA and protein abundance of different enzymes and receptors. Intramuscular (IM) and subcutaneous (SC) preadipocytes and bovine satellite cells were isolated from the longissimus muscle to determine the effect of treatment on ...
Tokach, Rebecca J. +4 more
openaire +3 more sources
Rosiglitazone-induced PPARγ activation promotes intramuscular adipocyte adipogenesis of pig
Animal Biotechnology, 2023 Intramuscular fat (IMF) positively influences various aspects of meat quality, while the subcutaneous fat (SF) has negative effect on carcass characteristics and fattening efficiency. Peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of adipocyte differentiation, herein, through bioinformatic screen for the potential ...
Zhaolu Wang +6 more
openaire +2 more sources
ACSL4 Directs Intramuscular Adipogenesis and Fatty Acid Composition in Pigs
Animals, 2022 The intramuscular fat is a major quality trait of meat, affecting sensory attributes such as flavor and texture. Several previous GWAS studies identified Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) gene as the candidate gene to regulate ...
Hongyan Ren +8 more
doaj +1 more source
Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]
, 2020 Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R. +6 more
core +1 more source
Integrative Adipogenic Engineering of Cultured Fat for Cell Based Meat. [PDF]
Compr Rev Food Sci Food SafABSTRACT Adipose tissue is a key determinant of the sensory, nutritional, and functional qualities of meat, yet its faithful replication in vitro remains one of the central challenges for cultured meat production. This review first examines the roles of fat in conventional meat, encompassing its contributions to flavor, texture, and nutritional value ...
Lee YS, Lee HJ, Jo C.
europepmc +2 more sources
Circ_0011446 Regulates Intramuscular Adipocyte Differentiation in Goats via the miR-27a-5p/FAM49B Axis. [PDF]
Int J Mol SciIntramuscular fat (IMF), or marbling, is a critical indicator of goat meat quality. Non-coding RNAs play a key role in the formation and deposition of IMF in vertebrates by regulating genes involved in its synthesis, degradation, and transport. The competing endogenous RNA (ceRNA) hypothesis identifies circular RNAs (circRNAs) as natural “sponges” for ...
Wang JM +7 more
europepmc +3 more sources
miR-214-5p Regulating Differentiation of Intramuscular Preadipocytes in Goats via Targeting KLF12
Frontiers in Genetics, 2021 Intramuscular fat (i.m.) is an adipose tissue that is deposited between muscle bundles. An important type of post-transcriptional regulatory factor, miRNAs, has been observed as an important regulator that can regulate gene expression and cell ...
Yu Du +13 more
doaj +1 more source
Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]
, 2020 Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D. +7 more
core +2 more sources