Results 141 to 150 of about 39,783 (286)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Volume and intramuscular fat content of upper extremity muscles in individuals with chronic hemiparetic stroke [PDF]

, 2019
Lindsay R. P. Garmirian, Ana Marı́a Acosta, R. Schmid, Julius P. A. Dewald   +3 more
openalex   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis, Ada S. Cheung, Brendan J. Nolan   +2 more
wiley   +1 more source

Reining in strangles: Absence of disease in horses vaccinated with a DIVA‐compatible recombinant fusion protein vaccine, Strangvac, following natural exposure to Streptococcus equi subspecies equi

Equine Veterinary Journal, EarlyView.
Abstract Background Strangles, caused by Streptococcus equi subspecies equi (S. equi), is a prevalent infectious disease of horses. This is the first report on the use of a new vaccine, Strangvac, in a natural outbreak of strangles. Objectives To measure the effects of Strangvac vaccination during an outbreak of strangles at a Swedish farm.
Gittan Gröndahl, Francesco Righetti, Anna Aspán, Joakim Bjerketorp, Sara Frosth, Lars Frykberg, Karin Jacobsson, Bengt Guss, Romain Paillot, Jan‐Ingmar Flock, Birgitta Henriques‐Normark, Andrew S. Waller   +11 more
wiley   +1 more source

Growth performance, carcass characteristics and meat palatability attributes in steers of various beef breeds compared at a similar level of intramuscular fat content

, 2001
A. Chambaz
openalex   +2 more sources

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, EarlyView.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source

Integrated lipidomic and transcriptomic analysis of intramuscular fat deposition in yellow-feathered broilers. [PDF]

Poult Sci
Li Z, Malyar RM, Sun H, Ding W, Li Y, Lu L, Shi F.   +6 more
europepmc   +1 more source

RNA N6-methyladenosine profiling reveals differentially methylated genes associated with intramuscular fat metabolism during breast muscle development in chicken

, 2023
Baojun Yu, Jiamin Liu, Zhengyun Cai, Haorui Wang, Xiaofang Feng, Tong Zhang, Ruoshuang Ma, Yaling Gu, Juan Zhang   +8 more
openalex   +1 more source

Microbial and Genomic Information Synergistically Contribute to Predicting Swine Performance Across Production Systems

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Microbiota composition represents a promising tool in precision farming, simultaneously serving as a benchmark of environmental challenge, a predictor of animal physiological status, and a direct target for host selection. In this paper, we compared the ability of microbiota composition and genomic information to predict swine performance in ...
Christian Maltecca, Enrico Mancin, Jicai Jiang, Maria Chiara Fabbri, Riccardo Bozzi, Clint Schwab, Francesco Tiezzi   +6 more
wiley   +1 more source