Results 221 to 230 of about 82,486 (300)

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima   +17 more
wiley   +1 more source

Myosteatosis Predicts Poor Prognosis in Patients With Castration‐Resistant Prostate Cancer Treated With Enzalutamide

open access: yesInternational Journal of Urology, Volume 33, Issue 5, May 2026.
ABSTRACT Objectives Prostate cancer prognostication has traditionally emphasized tumor‐related factors (e.g., Gleason score and metastatic burden). Emerging evidence suggests that physical (host) factors influence outcomes. This study evaluated whether physical factors, including myosteatosis and sarcopenia, are prognostic factors in patients with ...
Tomohiro Kanaki   +18 more
wiley   +1 more source

Impact of Model Parameterisation and Variance Component Estimates on Genomic Predictions of Carcass Traits in Montana Composite Cattle

open access: yesJournal of Animal Breeding and Genetics, Volume 143, Issue 3, Page 431-442, May 2026.
ABSTRACT This study evaluated the influence of variance component (VC) estimates, obtained from different models and two relationship matrices, pedigree‐based (BLUP) and genomic information‐based (ssGBLUP), on genomic predictions of carcass traits in Montana composite cattle.
Caroline Assis Almeida   +9 more
wiley   +1 more source

Integrating intramuscular fat radiomics with hamstrings-to-quadriceps structure and function ratios to predict future hamstring strain injury. [PDF]

open access: yesPLOS Digit Health
Sharma A   +16 more
europepmc   +1 more source

Effects of GLP‐1 Receptor Agonists on Muscle Mass, Strength, and Quality in MASLD: A Systematic Review

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims GLP‐1 receptor agonists (GLP‐1RAs) promote significant weight loss, but their impact on muscle mass, strength, and quality in metabolic dysfunction–associated steatotic liver disease (MASLD), a condition prone to muscle impairment, remains uncertain.
Fernando Iorra   +5 more
wiley   +1 more source

Mitochondrial β‐carbonic anhydrase is a conserved metabolic rheostat for branched‐chain amino acid catabolism and metabolic flexibility

open access: yesNew Phytologist, Volume 250, Issue 4, Page 2415-2427, May 2026.
Summary Carbonic anhydrases (CAs) are ubiquitous metalloenzymes that catalyze the reversible hydration of CO2, enabling fundamental processes in organisms across all domains of life. Among all CAs, the role of mitochondrial βCA remains poorly understood. Here, we identify a mitochondrial βCA, βCA6, as a key regulator of branched‐chain amino acid (BCAA)
Naveen Sharma   +2 more
wiley   +1 more source

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