Results 111 to 120 of about 1,950,206 (296)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Effect of Repeated Intranasal Administration of Different Doses of Insulin on Postoperative Delirium, Serum τ and Aβ Protein in Elderly Patients Undergoing Radical Esophageal Cancer Surgery

, 2023
Qingqing Huang,1 Qin Shi,2 Xiaobo Yi,1 Jingzheng Zeng,2 Xuemei Dai,1 Lu Lin,1 Yanling Yang,1 Xiao Wu,2 Gu Gong1 1Department of Anesthesiology, The General Hospital of Western Theater Command, Chengdu, People’s Republic of China; 2Department of ...
Yi X, Yang Y, Shi Q, Zeng J, Huang Q, Lin L, Dai X, Wu X, Gong G   +8 more
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Beyond antimicrobials: Ecological nano‐strategies for rebalancing dysbiotic oral microbial homeostasis

BMEMat, EarlyView.
Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu, Aohan Luan, Yujun Yang, Linlin Wang, Huilin Wang, Ning Wang, Guixin He, Yajie Yang, Rabiya Noor, Jawad Hussain, Longquan Shao   +10 more
wiley   +1 more source

First-in-human intranasal [13N]oxytocin PET: evaluation of feasibility, biodistribution, and radiation dosimetry

EJNMMI Research
Background Oxytocin is a neuropeptide with therapeutic potential for several neuropsychiatric and pain-related disorders. Intranasal delivery is proposed to enable access to the central nervous system via the trigeminal nerve and olfactory nerves ...
Michael Winterdahl, Erik Nguyen Nielsen, Søren B. Hansen, André Henrique Dias, Mikkel Holm Vendelbo, Steen Jakobsen, David Yeomans   +6 more
doaj   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Immunogenicity of HIV Virus-Like Particles in Rhesus Macaques by Intranasal Administration

, 2012
Female rhesus macaques were immunized with HIV virus-like particles (HIV-VLPs) or HIV DNA administered as sequential combinations of mucosal (intranasal) and systemic (intramuscular) routes, according to homologous or heterologous prime-boost schedules ...
Schroeder, Ulf, Schroeder, Ulf,, Lewis, M, Torneselloa, Maria Lina,, Pal, R, Pal, Ranajit, Wahren, B,, Tagliamonte, Maria,, Buonaguro, Luigi,, Visciano, ML, Tornesello, ML, Wahren, Britta, Tagliamonte, Maria, Andersen, H, Andersen, Hanne,, Pal, Ranajit,, Tagliamonte, M, Andersen, Hanne, Lewis, Mark,, Visciano, Maria Luisa, Hinkula, J, Visciano, Maria Luisa,, Hinkula, Jorma,, Wahren, Britta,, Buonaguro, Franco M.,, Buonaguro, L, Buonaguro, Luigi, Schroeder, U, Lewis, Mark, Torneselloa, Maria Lina, Hinkula, Jorma, Buonaguro, Franco M.   +31 more
core   +1 more source

Outcomes of out‐of‐hospital treatment of impending tonic–clonic status epilepticus with diazepam nasal spray: A retrospective combined cohort analysis

Epilepsia, EarlyView.
Abstract Objective We assessed the timing, dosing, and effectiveness of diazepam nasal spray in a large dataset of seizures treated in the out‐of‐hospital setting, using as reference the International League Against Epilepsy criteria for tonic–clonic status epilepticus (SE) and its treatment.
John M. Stern, Leock Y. Ngo, Eric B. Segal, Danielle A. Becker, Randa G. Jarrar, Tracy A. Glauser, Jurriaan M. Peters, Emilio Perucca, Evelyn K. Shih, Enrique Carrazana, Adrian L. Rabinowicz   +10 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Prescriptions for seizure cluster rescue therapy are not associated with decreased pediatric ED utilization

Epilepsia Open, EarlyView.
Abstract Objective Seizure clusters, or acute repetitive seizures, are a phenomenon often experienced by patients with epilepsy and pose a significant treatment challenge for clinicians. Several rescue medications have been approved by the Food and Drug Administration for the treatment of seizure clusters – including diazepam rectal gel, intranasal ...
Sarah A. Mangold, Mariah Eisner, Gabrielle Brown‐Mitchell, Christopher W. Beatty, Stephanie M. Ahrens, Jamie E. Twanow, Adam P. Ostendorf   +6 more
wiley   +1 more source

Influenza (flu) vaccine (live, intranasal) : what you need to know [Spanish]

Influenza (flu) vaccine (live, intranasal) : what you need to know [Spanish]Influenza (live, intranasal) VIS \u2013 Spanish (8/6/21)spanish_flu_live ...

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