Results 311 to 320 of about 57,277 (349)
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Intranasal drug delivery for treatment of Alzheimer’s disease
Drug Delivery and Translational Research, 2021The Alzheimer's disease is a neurodegenerative condition with severe consequences interfering with patient quality of life. It is characterized as a progressive and irreversible brain disorder hampering memory and thinking, affecting the capacity to perform daily tasks leading to physical and cognitive incapacitation.
Fonseca, Leonor Cancela +6 more
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Lipid Nanoparticles for Nasal/Intranasal Drug Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, 2017Studies on the development of drug delivery systems have increased because these systems have particular characteristics that allow them to improve therapeutics. Among these, lipid nanoparticles (solid lipid nanoparticles, SLNs; and nanostructured lipid carriers, NLCs) have demonstrated suitability for drug targeting.
Cunha, S. +3 more
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Intranasal Delivery of Nicardipine in the Rat
Journal of Pharmaceutical Sciences, 1986The intranasal absorption of nicardipine hydrochloride was characterized in an in vivo rat model system in which the normal mechanisms of mucociliary clearance and drainage of an instilled dose were not physically altered. The results obtained in this manner, therefore, are expected to be predicative of the delivery and absorption dynamics exhibited in
G C, Visor, E, Bajka, E, Benjamin
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Advanced formulations for intranasal delivery of biologics
International Journal of Pharmaceutics, 2018The global biologics market has been ever increasing over the last decades and is predicted to top Euro 350 by 2020. Facing this scenario, the parenteral route of biologics administration as hitherto standard route is inconvenient for the future. Among the alternatives, the intranasal delivery of therapeutic biologicals seems to be most promising but ...
Julia, Rohrer +2 more
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Intranasal Delivery of Nanoparticles
Nanomedicine, 2022Ralf P Friedrich +6 more
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Clinical Pharmacokinetics, 1989
Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
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Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
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Therapeutic Intranasal Delivery for Alzheimer’s Disease
2019Alzheimer’s disease (AD) is an age-related detrimental neurodegenerative disorder with no effective treatment, which is clinically characterized by progressive memory decline and cognitive dysfunction, altered decision making, apraxia, language disturbances, etc., and often histologically manifested by the deposition of amyloid-beta (Aβ) plaques and ...
Xinxin Wang, Fangxia Guan
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Vesicular Systems for Intranasal Drug Delivery
2009Recently, the nasal route for systemic drug delivery has gained great interest. It provides several advantages over other routes of drug administrations. These include rapid absorption, avoidance of the intestinal and hepatic AQ1 presystemic disposition, and high potential for drug transfer to the cerebrospinal fluid.
Ibrahim A. Alsarra +3 more
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Planning for post‐pandemic cancer care delivery: Recovery or opportunity for redesign?
Ca-A Cancer Journal for Clinicians, 2021Pelin Cinar +2 more
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