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Therapeutic Intranasal Delivery for Alzheimer’s Disease
2019Alzheimer’s disease (AD) is an age-related detrimental neurodegenerative disorder with no effective treatment, which is clinically characterized by progressive memory decline and cognitive dysfunction, altered decision making, apraxia, language disturbances, etc., and often histologically manifested by the deposition of amyloid-beta (Aβ) plaques and ...
Xinxin Wang, Fangxia Guan
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Vesicular Systems for Intranasal Drug Delivery
2009Recently, the nasal route for systemic drug delivery has gained great interest. It provides several advantages over other routes of drug administrations. These include rapid absorption, avoidance of the intestinal and hepatic AQ1 presystemic disposition, and high potential for drug transfer to the cerebrospinal fluid.
Ibrahim A. Alsarra +3 more
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Planning for post‐pandemic cancer care delivery: Recovery or opportunity for redesign?
Ca-A Cancer Journal for Clinicians, 2021Pelin Cinar, Daniela A Bota, Emad Elquza
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Intranasal insulin delivery and therapy.
Advanced drug delivery reviewsIntranasal insulin delivery has been widely investigated as an alternative to subcutaneous injection for the treatment of diabetes. The pharmacokinetic profile of intranasal insulin is similar to that obtained by intravenous injection and, in contrast to subcutaneous insulin delivery, bears close resemblance to the 'pulsatile' pattern of endogenous ...
, Hinchcliffe, , Illum
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Intranasal drug delivery: opportunities and toxicologic challenges during drug development
Drug Delivery and Translational Research, 2021Olivia M Merkel
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Intranasal drug delivery for systemic medications.
Critical reviews in therapeutic drug carrier systems, 1988This article is designed to provide a critical literature review on the scientific advances in intra- and transnasal drug delivery for systemic medication. The article discusses the fundamentals, developmental concepts, and biomedical assessment of the transnasal administration of systemically effective drugs which are either easily inactivated when ...
Y W, Chien, S F, Chang
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