Results 281 to 290 of about 57,259 (320)
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Intranasal Delivery of Nanoparticle-Based Vaccines
Therapeutic Delivery, 2017Most pathogens gain access to the human body and initiate systemic infections through mucosal sites. A large number of currently marketed licensed vaccines are parenterally administered; they generate strong systemic immunity but not mucosal immunity.
Marasini, Nirmal +2 more
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Intranasal delivery of tenoxicam in rat
International Journal of Pharmaceutics, 2001Intranasal delivery of tenoxicam was studied in male rats on single dose administration of 0.36 mg/rat and compared with intravenous administration. Tenoxicam plasma levels were determined by RP-HPLC method with UV detection that employed piroxicam as an electroactive internal standard in the analysis.
C V, Raghavan, V D, Abimon
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Focused ultrasound mediated intranasal delivery
The Journal of the Acoustical Society of America, 2021This presentation will introduce that focused ultrasound combined with intranasal delivery can achieve locally enhanced delivery of anti-programmed cell death-ligand 1 antibody to an intracranial murine glioma model.
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Intranasal delivery of vaccines against HIV
Expert Opinion on Drug Delivery, 2006HIV poses a serious health threat in the world. Mucosal transmission of HIV through the genitourinary tract may be the most important route of transmission. Intranasal immunisations induce vaginal and systemic immune responses. Various protein-, DNA- and RNA-based immunopotentiating adjuvants/delivery systems and live bacterial and viral vectors are ...
Michael, Vajdy, Manmohan, Singh
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Intranasal drug delivery for treatment of Alzheimer’s disease
Drug Delivery and Translational Research, 2021The Alzheimer's disease is a neurodegenerative condition with severe consequences interfering with patient quality of life. It is characterized as a progressive and irreversible brain disorder hampering memory and thinking, affecting the capacity to perform daily tasks leading to physical and cognitive incapacitation.
Fonseca, Leonor Cancela +6 more
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Lipid Nanoparticles for Nasal/Intranasal Drug Delivery
Critical Reviews™ in Therapeutic Drug Carrier Systems, 2017Studies on the development of drug delivery systems have increased because these systems have particular characteristics that allow them to improve therapeutics. Among these, lipid nanoparticles (solid lipid nanoparticles, SLNs; and nanostructured lipid carriers, NLCs) have demonstrated suitability for drug targeting.
Cunha, S. +3 more
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Intranasal Delivery of Nicardipine in the Rat
Journal of Pharmaceutical Sciences, 1986The intranasal absorption of nicardipine hydrochloride was characterized in an in vivo rat model system in which the normal mechanisms of mucociliary clearance and drainage of an instilled dose were not physically altered. The results obtained in this manner, therefore, are expected to be predicative of the delivery and absorption dynamics exhibited in
G C, Visor, E, Bajka, E, Benjamin
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Advanced formulations for intranasal delivery of biologics
International Journal of Pharmaceutics, 2018The global biologics market has been ever increasing over the last decades and is predicted to top Euro 350 by 2020. Facing this scenario, the parenteral route of biologics administration as hitherto standard route is inconvenient for the future. Among the alternatives, the intranasal delivery of therapeutic biologicals seems to be most promising but ...
Julia, Rohrer +2 more
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Intranasal Delivery of Nanoparticles
Nanomedicine, 2022Ralf P Friedrich +6 more
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Clinical Pharmacokinetics, 1989
Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
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Utilisation de la forme intranasale pour administrer les hormones peptides et d'autres medicaments.
A E, Pontiroli, A, Calderara, G, Pozza
openaire +2 more sources