Results 91 to 100 of about 3,438,764 (296)

Cell-Penetrating Peptides, Electroporation, and Drug Delivery

open access: yes, 2010
Certain short polycations, such as TAT and oligoarginine, rapidly pass through the plasma membranes of mammalian cells by a mechanism called transduction, as well as by endocytosis and macropinocytosis.
Cahill, Kevin
core   +1 more source

A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley   +9 more
wiley   +1 more source

Urothelial bladder carcinoma metastasizing to the eye: a systematic review and case report [PDF]

open access: yes, 2019
The eye is a rare site for disseminated malignancies; nevertheless, several tumors may metastasize to ocular structures. Few cases of urothelial and bladder cancer with eye involvement have been described in the literature thus far.
Brunelli, Matteo   +12 more
core   +1 more source

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

open access: yesVIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng   +14 more
wiley   +1 more source

Granulocytic Sarcoma as the First Sign of Acute Leukemia in Childhood [PDF]

open access: yes, 2012
Acute myeloid leukemia (AML) may rarely involve the orbit as a solid tumor termed granulocytic sarcoma. This report describes the case of a child who presented with rapidly progressive unilateral proptosis and was diagnosed as rhabdomyosarcoma.
Singh, T, Sufi, AR
core   +1 more source

Cystatin C and lactoferrin concentrations in biological fluids as possible prognostic factors in eye tumor development [PDF]

open access: yes, 2013
Objectives. To investigate the possible role of cystatin C in eye biological fluids locally and in serum and lactoferrin revealing anti-tumor activity in eye tumor development. Background.
Ananthi S   +19 more
core   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

open access: yesActa Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano   +26 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

open access: yesActa Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry   +27 more
wiley   +1 more source

Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma [PDF]

open access: yes, 2013
PurposeRetinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option.
Abramson   +26 more
core   +1 more source

Th17 Cells Are Involved in the Local Control of Tumor Progression in Primary Intraocular Lymphoma

open access: yesPLoS ONE, 2011
Background Th17 cells play an important role in the pathogenesis of many autoimmune diseases, but despite some reports of their antitumor properties, too little is known about their presence and role in cancers.
C. Galand   +8 more
semanticscholar   +1 more source

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