Results 61 to 70 of about 502,860 (198)
Peritoneal spread of tumors is a major problem in cancer management. Patients develop a marked deterioration in quality of life and shortened survival. This is in part due to bowel obstructions, marked ascites, and overall increase debilitation. Standard medical management has shown to be inadequate for the treatment of these problems.
Martin D, Goodman +3 more
openaire +1 more source
Laura M Enomoto, Perry Shen, Edward A Levine, Konstantinos I VotanopoulosWake Forest Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USAAbstract: Malignant peritoneal mesothelioma (MPM) is a rare, aggressive malignancy that ...
Enomoto LM +3 more
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Background/Objectives: Peritoneal metastases (PMs) remain difficult to treat because the peritoneum–plasma barrier limits drug penetration from the systemic circulation.
Kohei Tamura +7 more
doaj +1 more source
Intraperitoneal chemotherapy in the management of ovarian cancer: focus on carboplatin
Maurie MarkmanUniversity of Texas MD Anderson Cancer Center, Houston, Texas, USAAbstract: Both pre-clinical studies and phase 1–2 clinical trials have provided strong support for the potential role of regional drug delivery in the management of
Maurie Markman
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Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is an aggressive, but increasingly utilised, treatment for advanced peritoneal malignancy.
Laoise Niamh Geoghegan
doaj +2 more sources
Intraperitoneal follicular dendritic cell sarcoma: Role of chemotherapy and bone marrow allotransplantation in locally advanced disease? [PDF]
We describe a case of a 44 year-old woman diagnosed with follicular dendritic cell sarcoma (FDCS). FDCS is a very rare disease affecting the dendritic antigen presenting cells and is often misdiagnosed.
De Saint Aubain, Nicolas +13 more
core +1 more source
Hsin-Hsien Yu,1,2 Yutaka Yonemura,3–5 Mao-Chih Hsieh,1,2 Akiyoshi Mizumoto,4 Satoshi Wakama,3 Chang-Yun Lu1,2 1Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 2Division of General Surgery ...
Wakama S +5 more
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IntroductionIntraperitoneal chemotherapy for ovarian cancer treatment has controversial benefits as most methodologies are associated with significant morbidity.
Marcelo Simonsen +9 more
doaj +1 more source
Perioperative intraperitoneal chemotherapy for peritoneal surface malignancy
The treatment of peritoneal surface malignancy mainly focuses on diffuse malignant peritoneal mesothelioma, pseudomyxoma peritonei from appendiceal cancer, and peritoneal dissemination from gastrointestinal and ovarian cancers.
Paul H Sugarbaker +7 more
core +1 more source
Clinical resistance to platinum chemotherapy in ovarian cancer [PDF]
Platinum drugs are the most active agents in ovarian cancer. Their cytotoxicty results from DNA crosslinking. High tumour response rates are seen, but 80 % of patients relapse. Major mechanisms of platinum resistance in patients remain to be established.
Newton, C., Newton, C
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