Results 61 to 70 of about 502,860 (198)

Chemotherapy for intraperitoneal use: a review of hyperthermic intraperitoneal chemotherapy and early post-operative intraperitoneal chemotherapy.

open access: yesJournal of gastrointestinal oncology, 2016
Peritoneal spread of tumors is a major problem in cancer management. Patients develop a marked deterioration in quality of life and shortened survival. This is in part due to bowel obstructions, marked ascites, and overall increase debilitation. Standard medical management has shown to be inadequate for the treatment of these problems.
Martin D, Goodman   +3 more
openaire   +1 more source

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for peritoneal mesothelioma: patient selection and special considerations

open access: yes, 2019
Laura M Enomoto, Perry Shen, Edward A Levine, Konstantinos I VotanopoulosWake Forest Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USAAbstract: Malignant peritoneal mesothelioma (MPM) is a rare, aggressive malignancy that ...
Enomoto LM   +3 more
core  

Combined Intraperitoneal and Systemic Chemotherapy for Peritoneal Metastases: Drug Delivery Concepts, Pharmacokinetics, and Clinical Applications: A Narrative Review

open access: yesPharmaceutics
Background/Objectives: Peritoneal metastases (PMs) remain difficult to treat because the peritoneum–plasma barrier limits drug penetration from the systemic circulation.
Kohei Tamura   +7 more
doaj   +1 more source

Intraperitoneal chemotherapy in the management of ovarian cancer: focus on carboplatin

open access: yes, 2009
Maurie MarkmanUniversity of Texas MD Anderson Cancer Center, Houston, Texas, USAAbstract: Both pre-clinical studies and phase 1–2 clinical trials have provided strong support for the potential role of regional drug delivery in the management of
Maurie Markman
core  

Optimising postoperative care after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

open access: yesAdvances in Perioperative Care
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is an aggressive, but increasingly utilised, treatment for advanced peritoneal malignancy.
Laoise Niamh Geoghegan
doaj   +2 more sources

Intraperitoneal follicular dendritic cell sarcoma: Role of chemotherapy and bone marrow allotransplantation in locally advanced disease? [PDF]

open access: yes, 2015
We describe a case of a 44 year-old woman diagnosed with follicular dendritic cell sarcoma (FDCS). FDCS is a very rare disease affecting the dendritic antigen presenting cells and is often misdiagnosed.
De Saint Aubain, Nicolas   +13 more
core   +1 more source

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal goblet cell carcinomas with peritoneal carcinomatosis: results from a single specialized center

open access: yes, 2017
Hsin-Hsien Yu,1,2 Yutaka Yonemura,3–5 Mao-Chih Hsieh,1,2 Akiyoshi Mizumoto,4 Satoshi Wakama,3 Chang-Yun Lu1,2 1Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 2Division of General Surgery ...
Wakama S   +5 more
core  

Peritoneal chemotherapy delivery systems for ovarian cancer treatment: systematic review of animal models

open access: yesFrontiers in Oncology
IntroductionIntraperitoneal chemotherapy for ovarian cancer treatment has controversial benefits as most methodologies are associated with significant morbidity.
Marcelo Simonsen   +9 more
doaj   +1 more source

Perioperative intraperitoneal chemotherapy for peritoneal surface malignancy

open access: yes, 2006
The treatment of peritoneal surface malignancy mainly focuses on diffuse malignant peritoneal mesothelioma, pseudomyxoma peritonei from appendiceal cancer, and peritoneal dissemination from gastrointestinal and ovarian cancers.
Paul H Sugarbaker   +7 more
core   +1 more source

Clinical resistance to platinum chemotherapy in ovarian cancer [PDF]

open access: yes, 2009
Platinum drugs are the most active agents in ovarian cancer. Their cytotoxicty results from DNA crosslinking. High tumour response rates are seen, but 80 % of patients relapse. Major mechanisms of platinum resistance in patients remain to be established.
Newton, C., Newton, C
core  

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