Intraplaque Neovascularization, CD68+ and iNOS2+ Macrophage Infiltrate Intensity Are Associated with Atherothrombosis and Intraplaque Hemorrhage in Severe Carotid Atherosclerosis [PDF]
Background: Atherosclerosis is a progressive disease that results from endothelial dysfunction, inflammatory arterial wall disorder and the formation of the atheromatous plaque.
Ioan Alexandru Balmos +9 more
doaj +8 more sources
Incremental clinical value of intraplaque neovascularization in predicting recurrent ischemic stroke [PDF]
Objective Carotid intraplaque neovascularization (IPN) detected by contrast‐enhanced ultrasound (CEUS) is a risk factor for recurrent ischemic stroke.
Liuping Cui +5 more
doaj +6 more sources
Mathematical modeling of intraplaque neovascularization and hemorrhage in a carotid atherosclerotic plaque [PDF]
Background Growing experimental evidence has identified neovascularization from the adventitial vasa vasorum and induced intraplaque hemorrhage (IPH) as critical indicators during the development of vulnerable atherosclerotic plaques.
Yan Cai, Jichao Pan, Zhiyong Li
doaj +8 more sources
Carotid Intraplaque Neovascularization and Future Vascular Events in Patients With Asymptomatic Carotid Stenosis [PDF]
Objective: Intraplaque neovascularization is a marker of plaque vulnerability and is used to predict the risk of future vascular events in patients with symptomatic carotid stenosis; however, its association with asymptomatic carotid stenosis has not ...
Liuping Cui +10 more
doaj +5 more sources
Added Clinical Value of Intraplaque Neovascularization Detection to Color Doppler Ultrasound for Assessing Ischemic Stroke Risk [PDF]
Liuping Cui,1,2 Ran Liu,1 Fubo Zhou,1 Yumei Liu,1 Bing Tian,1 Ying Chen,2,* Yingqi Xing1,3,4,* 1Department of Vascular Ultrasound, Xuanwu Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Neurology, The ...
Cui L +6 more
doaj +5 more sources
Relationship Between Serum Lipid Profiles and Carotid Intraplaque Neovascularization in a High–Stroke‐Risk Population: A Cross‐Sectional Study in China [PDF]
Background Evidence of the association between serum lipid profiles and intraplaque neovascularization (IPN) is still limited. We aimed to study the value of a novel Doppler method, superb microvascular imaging, in correlating serum lipid profiles and ...
Ying Wang +11 more
doaj +5 more sources
Improved stroke risk stratification in carotid atherosclerosis: integrating intraplaque neovascularization into Carotid Plaque-RADS [PDF]
Introduction This study evaluates whether IPN, as assessed by contrast-enhanced ultrasound (CEUS), enhances stroke risk stratification within the Carotid Plaque-RADS framework.
Zhe Huang +5 more
doaj +4 more sources
The association of lipoprotein(a) and intraplaque neovascularization in patients with carotid stenosis: a retrospective study [PDF]
Background Lipoprotein(a) is genetically determined and increasingly recognized as a major risk factor for arteriosclerotic cardiovascular disease.
Shuang Xia +6 more
doaj +5 more sources
Intraplaque neovascularization combined with plaque elasticity for predicting ipsilateral stroke in patients with asymptomatic mild carotid stenosis. [PDF]
Background Intraplaque neovascularization (IPN) is a biomarker for vulnerable atherosclerotic plaques and can be effectively visualized via contrast-enhanced ultrasound (CEUS).
Zhang L, Jia C, Gu S, Chen J, Wu R.
europepmc +3 more sources
Effect of evolocumab on the progression of intraplaque neovascularization of the carotid based on contrast-enhanced ultrasonography (EPIC study): A prospective single-arm, open-label study. [PDF]
Background and Purpose: The aim of this study was to explore the effect of half a year of evolocumab plus moderate-intensity statin treatment on carotid intraplaque neovascularization (IPN) and blood lipid levels.
Chen J +20 more
europepmc +4 more sources

