Results 91 to 100 of about 1,759 (164)

α-Tocopherol inhibits atherogenesis and improves cardiac function in mice independently of its antioxidant properties

Vascular Biology
The impact of α-tocopherol on atherosclerosis is unclear and controversial. While some studies suggest potential benefits, such as antioxidant properties that may reduce oxidative stress, other studies indicate no significant preventive effects.
Isabelle Coornaert, Annelies Breynaert, Nina Hermans, Guido R Y De Meyer, Wim Martinet   +4 more
doaj   +1 more source

RED BLOOD CELL, HEMOGLOBIN AND HEME IN THE PROGRESSION OF ATHEROSCLEROSIS

Frontiers in Physiology, 2014
For decades plaque neovascularization was considered as an innocent feature of advanced atherosclerotic lesions, but nowadays growing evidence suggest that this process triggers plaque progression and vulnerability.
Viktória eJeney, Viktória eJeney, György eBalla, György eBalla, József eBalla   +4 more
doaj   +1 more source

Head-to-Head Comparison of Inflammation and Neovascularization in Human Carotid Plaques: Implications for the Imaging of Vulnerable Plaques.

, 2017
BACKGROUND: Inflammation and intraplaque neovascularization are acknowledged to be 2 features of plaque vulnerability, although their temporal expression and their respective value in predicting clinical events are poorly understood.
Caroline Bouzin, Robert Verhelst, Demeure, Fabian, Bouzin, Caroline, Parla Astarci, Anne-Catherine Pouleur, Roelants, Véronique, Bol, Anne, Jean-Louis J. Vanoverschelde, David Vancraeynest, Vancraeynest, David, Pouleur, Anne-Catherine, Christophe de Meester, Vanoverschelde, Jean-Louis, Gerber, Bernhard, Anne Bol, Astarci, Parla, Pasquet, Agnes, Bernhard L. Gerber, Fabian Demeure, de Meester de Ravenstein, Christophe, Verhelst, Robert, Véronique Roelants, Agnès Pasquet   +23 more
core   +1 more source

Current status and advances in ultrasound evaluation of neovascularization within carotid artery plaques: a systematic review

Cardiovascular Ultrasound
Vulnerable plaques are significant risk factors for acute ischemic events, and intraplaque neovascularization (IPN) is an important indicator for evaluating plaque vulnerability.
Yang Yang, Fangqin Liu, Jiaojun Yan, Yunhao Luo, Qiuyun Huang, Lang Qiao   +5 more
doaj   +1 more source

The role of contrast-enhanced ultrasound in risk assessment of carotid atheroma [PDF]

Romanian Journal of Military Medicine, 2016
Background and objective: Contrast-enhanced ultrasound, used to assess atherosclerotic carotid plaques, improves visualization of vessel wall irregularities and depicts intraplaque neovascularization.
Silviu Stanciu, Cristina Enciu, Ioana Răduţă, Dan Stoicescu, Adrian Anghel, Daniela Anghel, B. Olan, Lucian Ciobîcă   +7 more
doaj  

The value of contrast-enhanced ultrasound in assessing carotid plaque vulnerability and predicting stroke risk

Scientific Reports
The presence of vulnerable carotid plaques plays a critical role in ischemic stroke pathogenesis, with intraplaque neovascularization (IPN) serving as a key indicator of plaque instability.
Junjie Cao, Yuqi Zeng, Yang Zhou, Zhichao Yao, Ziyi Tan, Guijun Huo, Lili Zhang, Dayong Zhou   +7 more
doaj   +1 more source

99mTc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of atorvastatin treatment in ApoE−/− mice

Scientific Reports, 2017
Atherosclerotic neovascularization plays a significant role in plaque instability as it provides additional lipids and inflammatory mediators to lesions, and resulting in intraplaque hemorrhage. Vascular endothelial growth factor-A (VEGF-A) is considered
Hui Tan, Jun Zhou, Xiangdong Yang, Mieradilijiang Abudupataer, Xiao Li, Yan Hu, Jie Xiao, Hongcheng Shi, Dengfeng Cheng   +8 more
doaj   +1 more source

Plaque Neovascularization and Antiangiogenic Therapy for Atherosclerosis

, 2007
The concept that neovascularization of the vessel wall may play a fundamental role in the pathophysiology of atherosclerosis was proposed more than a century ago.
Caplice, Noel, Noel Caplice, Doyle, Brendan, Brendan Doyle   +3 more
core   +1 more source

Detection of adventitial vasa vasorum and intraplaque neovascularization in carotid atherosclerotic lesions with contrast-enhanced ultrasound and their role in atherosclerosis

, 2011
INTRODUCTION: The development of new surrogate markers of atherosclerosis is a crucial goal in the clinical setting, as they may allow physicians to recognize unstable lesions early and identify individuals with vulnerable or unstable lesions who bear an
Karimi, Sasan, Feinstein, Steven B., Partovi, Sasan, Zipp, Lisa, Staub, Daniel, Feinstein, Steven B, Loebe, Matthias, Noon, George P., Davies, Mark G, Davies, Mark G., Noon, George P   +10 more
core   +1 more source

Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study

Frontiers in Immunology
BackgroundUnstable atherosclerotic carotid plaques with intraplaque neovascularization (IPN) carry a substantial risk for ischemic stroke. Conventional ultrasound methods fall short in detecting IPN, where superb microvascular imaging (SMI) has emerged ...
Mahtab Zamani, Mahtab Zamani, Karolina Skagen, Karolina Skagen, Beate Lindberg, Vigdis Bjerkeli, Pål Aukrust, Pål Aukrust, Pål Aukrust, Bente Halvorsen, Bente Halvorsen, Mona Skjelland, Mona Skjelland   +12 more
doaj   +1 more source