Results 91 to 100 of about 24,723 (162)

The value of contrast-enhanced ultrasound in assessing carotid plaque vulnerability and predicting stroke risk

Scientific Reports
The presence of vulnerable carotid plaques plays a critical role in ischemic stroke pathogenesis, with intraplaque neovascularization (IPN) serving as a key indicator of plaque instability.
Junjie Cao, Yuqi Zeng, Yang Zhou, Zhichao Yao, Ziyi Tan, Guijun Huo, Lili Zhang, Dayong Zhou   +7 more
doaj   +1 more source

99mTc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of atorvastatin treatment in ApoE−/− mice

Scientific Reports, 2017
Atherosclerotic neovascularization plays a significant role in plaque instability as it provides additional lipids and inflammatory mediators to lesions, and resulting in intraplaque hemorrhage. Vascular endothelial growth factor-A (VEGF-A) is considered
Hui Tan, Jun Zhou, Xiangdong Yang, Mieradilijiang Abudupataer, Xiao Li, Yan Hu, Jie Xiao, Hongcheng Shi, Dengfeng Cheng   +8 more
doaj   +1 more source

Vasa vasorum and plaque neovascularization on contrast-enhanced carotid ultrasound imaging correlates with cardiovascular disease and past cardiovascular events

, 2010
BACKGROUND AND PURPOSE: Histological data associate proliferation of adventitial vasa vasorum and intraplaque neovascularization with vulnerable plaques represented by symptomatic vascular disease.
Feinstein, Steven B., Staub, Daniel, Johnson, Mahala, Espinosa, Paul, Ludden, David, Jaeger, Kurt A., Patel, Mita B., Tibrewala, Anjan, Coll, Blai   +8 more
core   +1 more source

Assessment of carotid atherosclerosis, intraplaque neovascularization, and plaque ulceration using quantitative contrast-enhanced ultrasound in asymptomatic patients with diabetes mellitus

, 2014
Aims Patients with diabetes mellitus (DM) are at severely increased risk of developing atherosclerosis. Intraplaque neovascularization (IPN) and plaque ulceration are markers of the vulnerable plaque, which is at an increased risk of rupture and may lead
Sijbrands, E.J.G.; id_orcid, Akkus, Z, van der Steen, Ton, Oord, Stijn, Renaud, G, Schinkel, Arend, Bosch, Hans, Sijbrands, E.J.G.   +7 more
core   +1 more source

Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study

Frontiers in Immunology
BackgroundUnstable atherosclerotic carotid plaques with intraplaque neovascularization (IPN) carry a substantial risk for ischemic stroke. Conventional ultrasound methods fall short in detecting IPN, where superb microvascular imaging (SMI) has emerged ...
Mahtab Zamani, Mahtab Zamani, Karolina Skagen, Karolina Skagen, Beate Lindberg, Vigdis Bjerkeli, Pål Aukrust, Pål Aukrust, Pål Aukrust, Bente Halvorsen, Bente Halvorsen, Mona Skjelland, Mona Skjelland   +12 more
doaj   +1 more source

Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation

Experimental and Molecular Medicine
The development of unstable carotid atherosclerotic plaques is associated with the induction of neutrophil extracellular traps (NETs) via the activation of diverse inflammatory mediators in the circulating bloodstream.
Yu Cao, Minghui Chen, Xinyu Jiao, Shuijie Li, Dong Wang, Yongxuan Zhan, Jiaju Li, Zhongfei Hao, Qingbin Li, Yang Liu, Yan Feng, Ruiyan Li, Hongjun Wang, Mingli Liu, Qiang Fu, Yongli Li   +15 more
doaj   +1 more source

Association between Pericytes in Intraplaque Neovessels and Magnetic Resonance Angiography Findings

, 2020
(1) Background: Pericytes are involved in intraplaque neovascularization of advanced and complicated atherosclerotic lesions. However, the role of pericytes in human carotid plaques is unclear. An unstable carotid plaque that shows high-intensity signals
Tatsuya Abe, Tomihiro Wakamiya, Shuji Sakata, Masashi Nishihara, Hiroyuki Irie, Jun Masuoka, Nobuaki Momozaki, Atsushi Ogata, Taichiro Mizokami, Tatsuya Tanaka   +9 more
core   +1 more source

A correlation study on triglyceride-glucose index and extensive neovascularization within carotid artery plaques

Diabetology & Metabolic Syndrome
Objective This study aims to investigate the correlation between the triglyceride-glucose (TyG) index and intraplaque neovascularization (IPN), evaluate the predictive efficacy of the TyG index for massive IPN, and provide novel serological markers for ...
Sen Wang, Yiqun Lin, Shuai Zheng, Yuyang Gan, Ying Liu, Yukang Zhang, Wen He, Wei Zhang   +7 more
doaj   +1 more source

VEGFR2 blockade reduces intraplaque haemorrhage and enhances plaque stability by augmentation of plaque neovessel maturation

, 2017
<p>Immature plaque neovessels contribute to atherosclerotic plaque instability and intraplaque haemorrhage by leaking erythrocytes and leukocytes in the plaque.
Paul Quax, Margreet de Vries (5366734), Erna Peters (5366740), Jaap Hamming (5366737), Marie-José Goumans (516094), Margreet de Vries, Erna Peters, Laura Parma, Marie-José Goumans, Laura Parma (5366743), Paul Quax (835172), Jaap Hamming   +11 more
core   +1 more source

Risk prediction for symptomatic ischemic cerebrovascular disease based on ultrasound indicators of carotid plaque neovascularization

Frontiers in Cardiovascular Medicine
ObjectiveTo construct a model for predicting the risk of symptomatic ischemic cerebrovascular disease (ICVD) based on carotid plaque characteristics utilizing Automated Machine Learning (AutoML) technology, systematically identify key predictive factors,
Jianmei Chen, Jia Wang, Qiushuang Wang, Wenqi Sun, Xiaoyan Huo, Xinna Li   +5 more
doaj   +1 more source