Results 101 to 110 of about 1,759 (164)

Neutrophil extracellular traps mediate the crosstalk between plaque microenvironment and unstable carotid plaque formation

Experimental and Molecular Medicine
The development of unstable carotid atherosclerotic plaques is associated with the induction of neutrophil extracellular traps (NETs) via the activation of diverse inflammatory mediators in the circulating bloodstream.
Yu Cao, Minghui Chen, Xinyu Jiao, Shuijie Li, Dong Wang, Yongxuan Zhan, Jiaju Li, Zhongfei Hao, Qingbin Li, Yang Liu, Yan Feng, Ruiyan Li, Hongjun Wang, Mingli Liu, Qiang Fu, Yongli Li   +15 more
doaj   +1 more source

Axitinib attenuates intraplaque angiogenesis, haemorrhages and plaque destabilization in mice

, 2018
: Aim: An increased density of intraplaque (IP) microvessels in ruptured versus nonruptured human plaques suggests that IP neovascularization has a major causative effect on plaque development and instability. Possibly, vascular endothelial growth factor
Martinet, Wim, De Meyer, Guido, Van der Veken, Bieke   +2 more
core  

Atherosclerotic plaque rupture and intraplaque hemorrhage do not correlate with symptoms in carotid artery stenosis

, 2003
ObjectivePreviously we failed to demonstrate a correlation between plaque type and symptoms in 165 carotid endarterectomy specimens. The purpose of this study was to analyze the relation between the anatomy of the carotid plaques and the presence of ...
Barrone, Andrea, Grana, Daniel R, Parodi, Juan C, Ferreira, Mariano, Milei, José, Matturri, Luigi   +5 more
core   +1 more source

Lonafarnib is a potential inhibitor for neovascularization.

PLoS ONE, 2015
Atherosclerosis is a common cardiovascular disease that involves the build-up of plaque on the inner walls of the arteries. Intraplaque neovacularization has been shown to be essential in the pathogenesis of atherosclerosis.
Linlin Sun, Songbo Xie, Guoyuan Peng, Jian Wang, Yuanyuan Li, Juan Qin, Diansheng Zhong   +6 more
doaj   +1 more source

Elastin fragmentation inatheroscleroticmice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death

, 2015
Aims There is a need for animal models of plaque rupture. We previously reported that elastin fragmentation, due to a mutation (C1039G(+/-)) in the fibrillin-1 (Fbn1) gene, promotes atherogenesis and a highly unstable plaque phenotype in apolipoprotein E
Van Der Linden, Anne-Marie, Verhoye, Marleen, De Meyer, Guido R. Y., Blockx, Ines, De Keulenaer, Gilles W., Roth, Lynn, Hervent, Anne-Sophie, Herman, Arnold G., Martinet, Wim, Bult, Hidde, Sluimer, Judith C.; id_orcid, Fransen, Paul, Lijnen, Henri R., De Keulenaer, Gilles, Van Hove, Cor E., De Meyer, Guido R.Y., Van Der Linden, Annemie, Herman, Arnold, Knaapen, Michiel W., Bauters, Dries, Schrijvers, Dorien M., Lijnen, Roger, Sluimer, Judith C., Van der Donckt, Carole, Vanhoutte, Greetje, De Meyer, Guido, Van Herck, Jozef L.   +26 more
core   +1 more source

Diagnostic accuracy of superb microvascular imaging for detecting intraplaque neovascularization: a systematic review and meta-analysis. [PDF]

Cardiovasc Diagn Ther, 2023
Zhao L, Han Y, Che Y, Zhang X, Luo M, Li J.   +5 more
europepmc   +1 more source

Associations of plaque morphology and location with Intraplaque neovascularization in the carotid artery by contrast-enhanced ultrasound imaging. [PDF]

Front Neurol, 2023
Gu SY, Zhang LN, Chen J, Li F, Yao MH, Jia CX, Wu R.   +6 more
europepmc   +1 more source

Image_1_Semaphorin 7A Promotes VEGFA/VEGFR2-Mediated Angiogenesis and Intraplaque Neovascularization in ApoE-/- Mice.tif

, 2018
Excessive neovascularization of atherosclerotic lesions increases plaque vulnerability and the susceptibility to rupture. Semaphorin 7A (Sema7A), a semaphorin family member, was recently reported to promote atherosclerotic plaque formation by mediating d-
Tao You (181123), Shuhong Hu (1632217), Yifei Liu (547021), Li Zhu (67404)   +3 more
core   +1 more source

Value of Intraplaque Neovascularization on Contrast-Enhanced Ultrasonography in Predicting Ischemic Stroke Recurrence in Patients With Carotid Atherosclerotic Plaque. [PDF]

Korean J Radiol, 2023
Huang Z, Cheng XQ, Liu YN, Bi XJ, Deng YB.   +4 more
europepmc   +1 more source

Segmental Heterogeneity of Vasa Vasorum Neovascularization in Human Coronary Atherosclerosis

, 2010
ObjectivesOur aim was to investigate the role of coronary vasa vasorum (VV) neovascularization in the progression and complications of human coronary atherosclerotic plaques.BackgroundAccumulating evidence supports an important role of VV ...
Hildebrandt, Heike A., Ritman, Erik L., Versari, Daniele, Gössl, Mario, Erbel, Raimund, Bajanowski, Thomas, Lerman, Amir, Sangiorgi, Giuseppe, Lerman, Lilach O.   +8 more
core   +1 more source