Results 61 to 70 of about 238,031 (160)

Initial Dose Tarlatamab–Associated Tumour Lysis Syndrome in Small Cell Lung Cancer: A Case Report

Respirology Case Reports, Volume 14, Issue 7, July 2026.
We report a fatal case of acute TLS following a single 1‐mg dose of tarlatamab in a patient with relapsed SCLC with extensive liver metastases. This case highlights the importance of TLS risk assessment prior to tarlatamab treatment. Extensive liver metastases and elevated lactate dehydrogenase levels may be risk factors for TLS in patients with SCLC ...
Katsuhiko Shibata, Hiromu Tanaka, Yusuke Arai, Yusuke Watanuki, Takashi Kokubo, Yo Watanabe, Shingo Nakayama, Takahiro Asami, Takashi Inoue   +8 more
wiley   +1 more source

Lobectomy for subsegmental lymph node metastasis of unknown origin [PDF]

, 2019
2019-02We report a very rare case of resected subsegmental lymph node metastasis of unknown origin. Hilar (N1) lymph node metastasis of unknown origin has previously been reported, but intrapulmonary lymph node metastasis has not been reported to date ...
Uchida, Osamu, Ikeda, Norihiko, Ichinose, Shuji, Yamaguchi, Gaku   +3 more
core   +1 more source

Unusual metachronous lung adenocarcinomas harboring EGFR L858R/T790M mutations: A case report

Thoracic Cancer, 2020
Multiple primary lung cancer (MPLC) is defined as two or more primary lung cancers occurring in the same patient and can be classified as synchronous multiple primary lung cancer (sMPLC) and metachronous multiple primary lung cancer (mMPLC).
Guotian Pei, Shanbo Cao, Yuqing Huang
doaj   +1 more source

Pleural Calcified Tumor Misdiagnosed as Peripheral Lung Cancer: A Case Report and Analysis of Imaging Differential Points

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Pleural calcified tumor. ABSTRACT Pleural calcified solitary fibrous tumor, though rare, should be considered in the differential diagnosis of peripheral lung nodules. Recognizing key imaging features such as broad‐based pleural attachment and coarse calcification can prevent misdiagnosis and avoid unnecessary lung resection, thereby preserving ...
Tengfang Zhang, Yilian Xie, Hao Chen, Qingyong Cai, Baolei liang, Zhengguo Wu   +5 more
wiley   +1 more source

First-Line EGFR-TKIs Treatment in Stage I Non-Small-Cell Lung Cancer Patients Harboring EGFR Gene Mutations with Postoperative Intrapulmonary Recurrence

Cancer Management and Research, 2021
Zhouyu Zhu, Ying Chai Department of Thoracic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence: Ying ChaiDepartment of Thoracic Surgery, The Second Affiliated ...
Zhu Z, Chai Y
doaj  

Evaluation of Photophysical Properties and Biological Applications of Diarylmethanes

ChemistryOpen, Volume 15, Issue 6, June 2026.
The wide applications of diarylmethanes were investigated through various experimental and computational approaches. The solvent environment influences the electronic properties of diarylmethanes and hence their drug‐like properties. Interactions with PARP1 revealed stable binding supporting anticancer potential.
H. Ranjini Jenifer, Fateh V. Singh, M. M. Balamurali   +2 more
wiley   +1 more source

Sarcomatoid Transformation of Pulmonary Mucinous Adenocarcinoma as a Mechanism of Immunotherapy Resistance

Thoracic Cancer, Volume 17, Issue 12, June 2026.
A patient with a pulmonary invasive mucinous adenocarcinoma (IMA) underwent a histological transformation into sarcomatoid carcinoma with multiple lymph node metastases following long‐term immunochemotherapy. BRAF D594G mutation was detected both at baseline and at the time of recurrence.
Kensuke Yanai, Tomohiro Tanaka, Konomi Kimura, Shinji Hirose, Hiroki Watanabe, Takaaki Masuda, Ryo Suzuki, Kohei Kushiro, Naohiro Yanagimura, Shuhei Kondo, Koichiro Nozaki, Yu Saida, Miyuki Sato, Satoshi Watanabe, Hajime Umezu, Koichi Hagiwara, Toshiaki Kikuchi   +16 more
wiley   +1 more source

Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]

, 2010
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Vinay Varadan, Hoon Kim, John Watkinson, Dimitris Anastassiou   +3 more
core  

Clinicopathological and Prognostic Disparities in Part‐Solid Versus Pure Solid Pulmonary Nodules as Early‐Stage Lung Adenocarcinoma

Thoracic Cancer, Volume 17, Issue 12, June 2026.
For clinical stage IA lung adenocarcinoma, part‐solid nodules (PSN) show lower CT‐solid value (−13.2 HU), less lymph node metastasis (11.2%), and better 5‐year recurrence‐free survival (87.6%) than pure solid nodules (SPN; 22.2 HU, 20.6%, 79.8%). Sublobar resection with limited nodal sampling appears safe for PSN, whereas SPN may require lobectomy and ...
Hanyue Li, Runhua Yu, Songyuan Guo, Yiyang Wang, Zhitao Gu, Wentao Fang   +5 more
wiley   +1 more source

Clinical characteristics, treatment response, and survival outcomes in melanoma patients with cavity carcinomatosis: A retrospective analysis

International Journal of Cancer, Volume 158, Issue 9, Page 2418-2428, 1 May 2026.
What's new? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin, Li Zhu, Yuyang Huang, Lizhu Chen, Yuping Lu, Yu Chen, Jing Lin   +6 more
wiley   +1 more source