Results 51 to 60 of about 83,573 (199)

Systemic and intrathecal baclofen produce bladder antinociception in rats

open access: yesBMC Urology, 2021
Background Baclofen, a clinically available GABAB receptor agonist, produces non-opioid analgesia in multiple models of pain but has not been tested for effects on bladder nociception.
Timothy J. Ness   +4 more
doaj   +1 more source

Look Before You Leap: When ITB Pumps Fail

open access: yesIndian Journal of Physical Medicine & Rehabilitation, 2022
A 32-year-old male presented with uncontrolled hip flexor spasms. He suffered a spinal cord injury and was put on an intrathecal baclofen pump. Despite escalating doses, his spasticity was not controlled.
Ravi Sankaran, Greeshma Varun
doaj   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal   +9 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

Effectiveness of Intrathecal Baclofen for Intractable Stiffperson Syndrome: a Case Report.

open access: yes, 2021
BACKGROUND: Intrathecal baclofen is considered an adjuvant therapy for patients with intractable spasms due to stiff-person syndrome. There is increasing evidence to support the use of intrathecal baclofen in the management of symptomatic stiffperson ...
van Why, David   +3 more
core   +1 more source

Intra-Arterial, but Not Intrathecal, Baclofen and Codeine Attenuates Cough in the Cat

open access: yesFrontiers in Physiology, 2021
Centrally-acting antitussive drugs are thought to act solely in the brainstem. However, the role of the spinal cord in the mechanism of action of these drugs is unknown.
Wendy L. Olsen   +5 more
doaj   +1 more source

Retraction of an intrathecal baclofen infusion catheter following suprapubic cystotomy: a case report. [PDF]

open access: yes, 2009
Contains fulltext : 81671.pdf (Publisher’s version ) (Open Access)INTRODUCTION: Intrathecal baclofen, administered via a Baclofen pump, is used for patients with spasticity.
Burg, M.J. van den   +9 more
core   +2 more sources

The contribution of tone to resting energy expenditure in children with moderate to severe cerebral palsy: Evaluation utilizing intrathecal baclofen injection

open access: yesJournal of Pediatric Rehabilitation Medicine, 2008
The extent to which high muscle tone contributes to the caloric needs of children with cerebral palsy (CP) is debated. Understanding its contribution is important in predicting calorie needs in this population which frequently experiences under nutrition.
Li-Fen Liu   +3 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Laparoscopic fundoplication for a child with abdominal intrathecal Baclofen pump [PDF]

open access: yes, 2020
This is the first case report describing a laparoscopic fundoplication in a child with an intrathecal Baclofen pump which was inserted because of severe spasticity secondary to cerebral palsy.
Tomioka, Yuichiro   +5 more
core   +1 more source

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