Results 51 to 60 of about 3,938 (215)
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
, 2017 Oral baclofen has long been a mainstay in the management of spasticity. This review looks at the clinical evidence for the efficacy and safety of oral baclofen in patients with spasticity of any origin or severity, to determine whether there is a ...
Ertzgaard, Per, +5 more
core +1 more source
Developmental Medicine &Child Neurology, EarlyView.Safety strategies used by adults with complex forms of cerebral palsy when participating in community‐based physical activity were explored in this study. Physical assistance was the main safety strategy in use, provided for four key purposes. The attributes of support people in community settings was key to experiences of safety.
Georgia B McKenzie +6 more
wiley +1 more source
Kaohsiung Journal of Medical Sciences, 2008 We report a case of intrathecal baclofen infusion pump implantation complicated by migration of the catheter tip. A 55-year-old man required an intrathecal baclofen infusion for severe spasticity 4 years after a cervical spinal cord injury with ...
Tung-Chou Li +5 more
doaj +1 more source
Intra-Arterial, but Not Intrathecal, Baclofen and Codeine Attenuates Cough in the Cat
Frontiers in Physiology, 2021 Centrally-acting antitussive drugs are thought to act solely in the brainstem. However, the role of the spinal cord in the mechanism of action of these drugs is unknown.
Wendy L. Olsen +5 more
doaj +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To identify the outcomes reported in published studies of intervention approaches used with non‐degenerative childhood hyperkinetic movement disorders, including dystonia, dyskinesia, hypertonia, athetosis, chorea, cerebral palsy, involuntary movement, and kernicterus, and map them to the International Classification of Functioning ...
Hortensia Gimeno +10 more
wiley +1 more source
Changes in body composition after spasticity treatment with intrathecal baclofen
, 2017 Objective: To assess changes in body composition, body weight and resting metabolic rate in patients who received intrathecal baclofen therapy for spasticity. Design: Prospective, longitudinal, quasi-experimental, with a pre/post design. Patients: Twelve
Ertzgaard, Per, +7 more
core +1 more source
Journal of Pediatric Rehabilitation Medicine, 2008 The extent to which high muscle tone contributes to the caloric needs of children with cerebral palsy (CP) is debated. Understanding its contribution is important in predicting calorie needs in this population which frequently experiences under nutrition.
Li-Fen Liu +3 more
doaj +1 more source
Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review
CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley +1 more source
Effectiveness of Intrathecal Baclofen for Intractable Stiffperson Syndrome: a Case Report.
, 2021 BACKGROUND: Intrathecal baclofen is considered an adjuvant therapy for patients with intractable spasms due to stiff-person syndrome. There is increasing evidence to support the use of intrathecal baclofen in the management of symptomatic stiffperson ...
van Why, David +3 more
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