Results 71 to 80 of about 83,573 (199)

Intrathecal baclofen toxicity in a patient with acute kidney injury

Journal of Pediatric Rehabilitation Medicine, 2019
A 9-year old male patient with a past medical history of congenital cytomegalovirus (CMV) infection and spastic quadriplegic cerebral palsy with an intrathecal baclofen pump was admitted to a tertiary care hospital with respiratory depression and ...
Angeline Bowman, Rita Ayyangar, Ian Gonzales, Joseph Hornyak   +3 more
doaj   +1 more source

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley   +1 more source

Efficacy and Safety of Baclofen 40 mg/20 mL in an Intrathecal Infusion System

Life
Background: Spasticity is a common feature of Upper Motoneuron Syndrome and is frequently treated with intrathecal baclofen (ITB) when oral therapy is ineffective or poorly tolerated. Different baclofen formulations are available for intrathecal use, but
Riccardo Marvulli, Serena Gervasi, Giuseppa Lagioia, Lucrezia Dell’Olio, Serena Caforio Montesardo, Marisa Megna, Maurizio Ranieri   +6 more
doaj   +1 more source

Surgical management of spasticity

Journal of Children's Orthopaedics, 2013
Intractable and severe spasticity in childhood has the ability to impact on the quality of life, function and care of the child. Where medical and physical measures have proved insufficient, a surgical approach may be pursued.
Andrew Roberts
doaj   +1 more source

Pharmacotherapy of Spasticity in Children With Cerebral Palsy

Journal of the Formosan Medical Association, 2011
Spasticity is a common disability in children with cerebral palsy. Pharmacological and non-pharmacological treatments, including physical therapy, occupational therapy, orthotics, rhizotomy, and orthopedic surgery, all play important roles in the ...
Chia-Ying Chung, Chia-Ling Chen, Alice May-Kuen Wong   +2 more
doaj   +1 more source

Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

Movement Disorders, Volume 41, Issue 7, Page 1704-1715, July 2026.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer, Volker Kittke, Alice Saparov, Alexej Knaus, Shimriet Zeidler, Rachel Schot, Florian Kraft, Matthias Begemann, Suzanna Koudijs, Ugo Sorrentino, Chen Zhao, Ivana Dzinovic, Martin Pavlov, Elisabeth Graf, Antonia M. Stehr, Peter M. Krawitz, Christian Wilhelm, Saskia Biskup, Fahd Alsalloum, Steffen Berweck, Juliane Winkelmann, Konrad Oexle, Ingo Kurth, G. Christoph Korenke, Michael Zech   +24 more
wiley   +1 more source

Intrathecal baclofen withdrawal: A rare cause of reversible cardiomyopathy.

, 2016
Baclofen is commonly used to treat spasticity of central etiology. Unfortunately, a potentially lethal withdrawal syndrome can complicate its use. This is especially true when the drug is administered intrathecally.
Nawaz, Yassir, Kitei, Paul M, Awuor, Stephen O, Ahnert, Amy M, MD   +3 more
core   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

Utilizing combination intrathecal baclofen and analgesic medication to manage spasticity and pain in patients with pediatric-onset disability: Case series

Journal of Pediatric Rehabilitation Medicine
PURPOSE: The use of intrathecal medications for the management of spasticity and various pain syndromes in the adult population has been previously reported. However, no evidence-based guidelines currently exist in the pediatric population.
Denesh Ratnasingam, Tess Woehrlen, Samantha Koerber, Emma Drenth, Neena Marupudi, Melisa Concepcion, Erika Erlandson   +6 more
doaj   +1 more source

Complex regional pain syndrome with associated chest wall dystonia: a case report

Journal of Brachial Plexus and Peripheral Nerve Injury, 2011
Patients with complex regional pain syndrome (CRPS) often suffer from an array of associated movement disorders, including dystonia of an affected limb.
Schwartzman Robert J, Irwin David J
doaj   +1 more source