Results 71 to 80 of about 3,938 (215)

Surgical management of spasticity

open access: yesJournal of Children's Orthopaedics, 2013
Intractable and severe spasticity in childhood has the ability to impact on the quality of life, function and care of the child. Where medical and physical measures have proved insufficient, a surgical approach may be pursued.
Andrew Roberts
doaj   +1 more source

Pharmacotherapy of Spasticity in Children With Cerebral Palsy

open access: yesJournal of the Formosan Medical Association, 2011
Spasticity is a common disability in children with cerebral palsy. Pharmacological and non-pharmacological treatments, including physical therapy, occupational therapy, orthotics, rhizotomy, and orthopedic surgery, all play important roles in the ...
Chia-Ying Chung   +2 more
doaj   +1 more source

Radial Extracorporeal Shock Wave Therapy for Lower‐Limb Spasticity in an Individual With Subacute Stroke: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Radial extracorporeal shock wave therapy showed immediate spasticity reduction and sustained range of motion improvement in a patient with subacute stroke. However, twice‐weekly sessions were insufficient for lasting spasticity control, suggesting that more frequent treatments may be required.
Daisuke Kato   +7 more
wiley   +1 more source

Treatment of motor and behavioural symptoms in three Lesch-Nyhan patients with intrathecal baclofen [PDF]

open access: yes, 2014
Current therapies for the Lesch-Nyhan Syndrome (OMIM: 300322) are off-label and experimental, often leading to inconsistent outcomes. We here report the effects of an intrathecal baclofen therapy, carried out at the Scientific Institute Eugenio Medea ...
Marco Pozzi   +11 more
core   +1 more source

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

open access: yesPM&R, Volume 18, Issue S1, Page S45-S55, February 2026.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae   +4 more
wiley   +1 more source

Outcomes of selective dorsal rhizotomy in ambulatory children and young people with cerebral palsy: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 2, Page 175-186, February 2026.
This scoping review highlights that in the selective dorsal rhizotomy (SDR) literature, the emphasis still remains on impairment‐based outcomes in the body function and structure domain of the ICF. However, there has been a small shift towards participation and quality‐of‐life outcomes in the last decade.
Deepti Chugh   +7 more
wiley   +1 more source

Complex regional pain syndrome with associated chest wall dystonia: a case report

open access: yesJournal of Brachial Plexus and Peripheral Nerve Injury, 2011
Patients with complex regional pain syndrome (CRPS) often suffer from an array of associated movement disorders, including dystonia of an affected limb.
Schwartzman Robert J, Irwin David J
doaj   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 21-35, January 2026.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim   +6 more
wiley   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

Blessing or burden? Long-term maintenance, complications and clinical outcome of intrathecal baclofen pumps [PDF]

open access: yes, 2018
Aim: The intrathecal baclofen pump is an effective treatment for spasticity. However, long-term results have reported patients’ dissatisfaction and perception of disability.
Wai-Sang Poon   +23 more
core   +1 more source

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