Results 41 to 50 of about 83,573 (199)

Severe Case of Oral Baclofen Withdrawal Resulting in Mechanical Ventilation

Journal of Investigative Medicine High Impact Case Reports, 2022
Abrupt baclofen withdrawal may be life-threatening with varied neuropsychiatric manifestations. We present a case of baclofen withdrawal necessitating intubation.
Resha Khanal, Sharad Oli, Janet Chan Gomez, Sahar Tahir, Binita Bhandari, Saketram Komanduri   +5 more
doaj   +1 more source

Treatment failure of intrathecal baclofen and supra-additive effect of nabiximols in multiple sclerosis-related spasticity: a case report

Therapeutic Advances in Neurological Disorders, 2013
Multiple sclerosis (MS)-related spasticity is associated with disability and impairment in quality of life. We report on a patient with secondary progressive MS and spastic tetraparesis (Expanded Disability Status Scale score 8.5).
Anke Stroet, Nadine Trampe, Andrew Chan
doaj   +1 more source

Intrathecal Baclofen for Severe Spasticity: Longitudinal Data From the Product Surveillance Registry

Neuromodulation (Malden, Mass.), 2020
To assist in the assessment of intrathecal baclofen (ITB) therapy risks and benefits by providing surgical intervention rate, safety, and elective device replacement rate data.
M. Schiess, S. Eldabe, P. Konrad, Lisa Molus, Robert J Spencer, K. Stromberg, T. Weaver, Robert J. Plunkett   +7 more
semanticscholar   +1 more source

Intrathecal Baclofen Pumps do not Accelerate Progression of Scoliosis in Quadriplegic Spastic Cerebral Plasy

Global Spine Journal, 2016
Introduction Intrathecal baclofen pumps are an effective treatment for spasticity in patients with cerebral palsy. Recently, concerns have been raised regarding the potential for intrathecal baclofen pumps to accelerate scoliosis progression and increase
Paul Rushton, Luigi Nasto, Ranjit Aujla, Michael Vloeberghs, Michael Grevitt   +4 more
doaj   +1 more source

Successful In Situ Management of Intrathecal Baclofen Pump-Associated Staphylococcus Epidermidis Meningitis: A Case Report

Clinical and Translational Neuroscience
Objective: Our objective was to report the successful in situ management of Staphylococcus epidermidis meningitis following intrathecal baclofen pump implantation without removing the device. Design: This was a single case report with clinical follow-up.
Elisa Grana, Victoria Saulnier, Jocelyne Bloch, Stefano Carda   +3 more
doaj   +1 more source

Severe, Protracted Spasm of Urinary Bladder and Autonomic Dysreflexia Caused by Changing the Suprapubic Catheter in a Cervical Spinal Cord Injury Patient: Treatment by a Bolus Dose and Increased Total Daily Dose of Intrathecal Baclofen

Clinical Medicine Insights: Case Reports, 2016
Background Intrathecal administration of baclofen by implanted pump reduces rigidity and muscle spasms. Its use specifically to control bladder spasms has not been reported.
Subramanian Vaidyanathan, Tun Oo, Bakul M. Soni, Peter L. Hughes, Gurpreet Singh   +4 more
doaj   +1 more source

Bladder stones – red herring for resurgence of spasticity in a spinal cord injury patient with implantation of Medtronic Synchromed pump for intrathecal delivery of baclofen – a case report

BMC Urology, 2003
Background Increased spasms in spinal cord injury (SCI) patients, whose spasticity was previously well controlled with intrathecal baclofen therapy, are due to (in order of frequency) drug tolerance, increased stimulus, low reservoir volume, catheter ...
Singh Gurpreet, Hughes Peter L, Oo Tun, Soni Bakul M, Vaidyanathan Subramanian, Watt John WH, Sett Pradipkumar   +6 more
doaj   +1 more source

Aseptic meningitis after intrathecal baclofen injection.

, 2006
International audienceStUDY DESIGN: Two case reports of aseptic meningitis after intrathecal baclofen injection. OBJECTIVES: To report an unusual complication of intrathecal baclofen injection during test injections.
Bussel, B., B Bussel, D Bensmail, L Bernard, Denys, P., A Peskine, P Denys, Peskine, Anne, Bensmail, D., Bernard, L.   +9 more
core   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

Movement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska, Maresa Buchholz, Audrey Iskandar, Marcus Grobe‐Einsler, Thomas Klockgether, Jennifer Faber, Bernhard Michalowsky   +6 more
wiley   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

Movement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source