Results 81 to 90 of about 64,466 (204)

Morphine Metabolism in Human Skin Microsomes [PDF]

, 2012
For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S., Küchler, S., Schäfer-Korting, Monika, Küchler, Sarah, Schäfer-Korting, M.   +4 more
core   +1 more source

Targeting exosomal double-stranded RNA-TLR3 signaling pathway attenuates morphine tolerance and hyperalgesia

Cell Reports Medicine
Summary: Long-term morphine use leads to tolerance and hyperalgesia in patients with chronic pain, with neuroinflammation playing a key role, but its underlying mechanisms remain elusive.
Bing Wang, Dong-Sheng Le, Li Liu, Xue-Xue Zhang, Fan Yang, Guo-Rong Lai, Chao Zhang, Mai-Lin Zhao, Yun-Peng Shen, Ping-Sheng Liao, Tong Liu, Ying-Ping Liang   +11 more
doaj   +1 more source

Intrathecal Morphine for Post-Thoracotomy Pain

Anesthesia & Analgesia, 1986
We wished to investigate possible differences in the duration of postoperative analgesia and the incidence of respiratory depression after the intrathecal injection in the lumbar area of 10 micrograms/kg morphine in hypobaric and hyperbaric solution for relief of post-thoracotomy pain.
J R, Gray, G A, Fromme, L A, Nauss, J K, Wang, D M, Ilstrup   +4 more
openaire   +3 more sources

A Prospective Randomized Dose-Finding Study of Intrathecal Opioids for Postoperative Analgesia After Minimally Invasive Colorectal Operation

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To determine the optimal dose of intrathecal morphine and hydromorphone in patients undergoing minimally invasive colorectal operation for postoperative analgesia. Patients and Methods: The study was a double-blinded clinical dosing trial that
Patrice A. Vinsard, MD, Josef Pleticha, MD, Emily E. Sharpe, MD, Jason K. Panchamia, DO, David A. Olsen, MD, Hans P. Sviggum, MD, Sherief F. Shawki, MB, MD, Kevin T. Behm, MD, David W. Larson, MD, MBA, Allison M. LeMahieu, MS, Adam D. Niesen, MD, Adam W. Amundson, MD   +11 more
doaj   +1 more source

Successful treatment of intrathecal morphine overdose

, 2003
A 47-year-old woman was diagnosed with secondary progressive multiple sclerosis, and was treated with intrathecal morphine for chronic pain via a slow-release subcutaneous pump.
A. Sögüt, M. Kílínç, A. G. Sögüt, A. Yílmaz   +3 more
core   +2 more sources

Prophylactic Intrathecal Morphine and Prevention of Post-Dural Puncture Headache A Randomized Double-blind Trial

, 2020
Background: Prophylactic epidural morphine administration after unintentional dural puncture with a large-bore needle has been shown to decrease the incidence of post-dural puncture headache.
Higgins, Nicole, McCarthy, Robert J., Jones, Mary Jane, Peralta, Feyce M., Wong, Cynthia A., Toledo, Paloma   +5 more
core   +1 more source

Is a Single Low Dose of Intrathecal Morphine a Useful Adjunct to Patient-Controlled Analgesia for Postoperative Pain Control Following Lumbar Spine Surgery? A Preliminary Report

Pain Research and Management, 2015
BACKGROUND: Several studies addressing intrathecal morphine (ITM) use following spine surgery have been published either involving the pediatric population, using mid- to high-dose ITM, or not in conjunction with morphine patient-controlled analgesia ...
David Yen, Kim Turner, David Mark
doaj   +1 more source

Can repeated exposure to morphine change the spinal analgesic effects of lidocaine in rats?

Journal of Research in Medical Sciences, 2011
Background: Chronic opium exposure leads to altered response to opioid compounds. The aim of this study was to assess the behavioral effects of opium tolerance on the analgesic effects of intrathecal lidocaine in rats.
Ali Dabbagh, Shervin Farkhondehkish Moghadam, Samira Rajaei, Zahra Mansouri, Homa Shardi Manaheji   +4 more
doaj  

Is transversus abdominis plane block universally effective after cesarean delivery? A systematic review and meta-analysis

Frontiers in Anesthesiology
BackgroundThe TAP block has gained wide acceptance in post-cesarean multimodal analgesia, yet its efficacy varies considerably depending on clinical context.
Efrain Riveros-Perez, Bibiana Avella-Molano   +1 more
doaj   +1 more source

Abstracts from the 2026 Congress of the Scandinavian Society of Anesthesiology and Intensive Care Medicine, Reykjavik, Iceland, June 10–12, 2026

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
wiley   +1 more source