Results 61 to 70 of about 64,466 (204)

Cancer‐related pain: A bidirectional modulator of cancer progression

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He   +5 more
wiley   +1 more source

Intrathecal Morphine Pump for Neuropathic Cancer Pain

open access: yes, 2011
The WHO ladder has been the most widely used approach for management of Cancer Pain. However, oral medications alone may be inadequate, particularly in difficult to treat cancer pain syndromes. Neuropathic pain is one of these refractory syndromes.
Vikas Gogia   +5 more
core   +1 more source

Influence of the Reproductive and Non‐Reproductive Season on Hepatic Fat Accumulation in Trachemys sp.: Correlations of Computed Tomography, Histopathology, Biochemistry and Coelioscopy

open access: yesAnatomia, Histologia, Embryologia, Volume 55, Issue 5, September 2026.
ABSTRACT The hepatic energy storage of twenty‐four freshwater turtles was assessed using computed tomography, 3D Slicer software, serum biochemistry and histopathological analysis of liver biopsies to investigate the influence of seasonality and sex. In the evaluated animal group, seasonality did not influence hepatic fat and glycogen stores; however ...
Luna S. Rolim   +7 more
wiley   +1 more source

Optimal intrathecal morphine dosing for revision hip arthroplasty: an observational study

open access: yes
Anaesthesia, EarlyView.
Shalini Patel   +4 more
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

open access: yesEquine Veterinary Education, Volume 38, Issue 8, Page 442-452, August 2026.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly   +4 more
wiley   +1 more source

The transversus abdominis plane block in conjunction with intrathecal morphine use after cesarean section in women with severe pre-eclampsia: a randomized controlled trial

open access: yesBMC Anesthesiology, 2023
Background The transversus abdominis plane (TAP) block in conjunction with intrathecal morphine has been demonstrated to provide more superior postcesarean analgesia to intrathecal morphine alone.
Zhi-rong Yan   +8 more
doaj   +1 more source

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley   +1 more source

Management of moderate pain after orthopaedic surgery: A multiregional expert consensus model for postoperative and discharge protocol development

open access: yesJournal of Experimental Orthopaedics, Volume 13, Issue 3, July 2026.
Virtual Nominal Group Technique (VNGT)‐derived framework providing a common ground to develop institutional pain management protocols after orthopedic surgery, were developed by three regional panels of expert. Pillars of pain management included systematic pain assessment, defined analgesic targets, multimodal analgesia centered on scheduled non ...
Gabriele Finco   +29 more
wiley   +1 more source

General Anaesthesia Versus Spinal Anaesthesia for Outpatient Total Hip and Knee Arthroplasty: A Randomised Trial Protocol

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction Same‐day discharge after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is increasing, but the optimal anaesthetic technique for outpatient pathways remains uncertain. Neuraxial anaesthesia is widely recommended based on observational evidence, whereas fast‐track programmes using short‐acting total ...
Erik Noppa   +6 more
wiley   +1 more source

17. Cancer Pain: Part I: Cordotomy for Unilateral Pain due to Cancer

open access: yesPain Practice, Volume 26, Issue 6, July 2026.
ABSTRACT Introduction Despite advancements in pharmacological and intrathecal treatment of oncological pain, it remains a significant challenge, affecting 44.5% of patients with cancer, with 30.6% experiencing moderate‐to‐severe pain. Methods This scoping review provides a summary of the literature from 2016 to 2024, focusing on percutaneous cordotomy ...
Bregje Huisman   +7 more
wiley   +1 more source

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