Results 41 to 50 of about 10,244 (214)

Intrathecal morphine slows gastrointestinal transit in rats [PDF]

, 1985
Intrathecal (i.th.) (by direct lumbar puncture) and intraperitoneal (i.p.) administration of morphine (30-100 [mu]g/rat) caused a dose-related inhibition of gastrointestinal transit in the rat. Pretreatment with i.th.
Gmerek, Debra E., Vaught, Jeffry L., Koslo, Randy J., Porreca, Frank, Cowan, Alan   +4 more
core   +1 more source

Comparative study between doses of intrathecal morphine for analgesia after caesarean

Brazilian Journal of Anesthesiology, 2013
Background and objectives: Analgesia after caesarean section is important because postpartum women with pain have difficulty in mobility, which undermines breastfeeding. Intrathecal morphine provides adequate and prolonged analgesia after cesarean.
Francisco Amaral Egydio de Carvalho, Sérgio B. Tenório   +1 more
doaj   +1 more source

Comparative Efficacy of 3 Adjuvant Medications Used in Combination with Intrathecal Bupivacaine for Caesarian Section Anesthesia: A Randomized, Double-Blind Clinical Trial

Current Therapeutic Research, 2022
: Background: A number of different medications are used in combination with intrathecal bupivacaine for cesarean section anesthesia, but their relative efficacy has not been well established.
Reza Jouybar, MD, Zeinabsadat Fattahi Saravi, MD, Nazi Dehghani, MD, Sara Sadeghi, MD, Sahar Chehelgerdi Samani, MD, Zahra Esmaeilinezhad, MSc, Farzaneh Masihi, MSc, Naeimehosadat Asmarian, PhD   +7 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Effect of intrathecal opioid dose variation on patient outcomes in cesarean sections on a remote Indonesian island: a randomized controlled trial

Вестник интенсивной терапии
INTRODUCTION: Intrathecal opioids are routinely used as adjuvants to spinal anesthesia for cesarean section to improve postoperative analgesia. While intrathecal morphine is considered the gold standard, the optimal dose that balances analgesic efficacy
Joshua Christian Suyanto, M. P. Nugroho, P. J. Nareswari   +2 more
doaj   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Neuraxial opioids as analgesia in labour, caesarean section and hysterectomy: A questionnaire survey in Sweden [version 2; referees: 2 approved]

F1000Research, 2017
Background: Neuraxial opioids improve labour analgesia and analgesia after caesarean section (CS) and hysterectomy. Undesirable side effects and difficulties in arranging postoperative monitoring might influence the use of these opioids.
Anette Hein, Caroline Gillis-Haegerstrand, Jan G. Jakobsson   +2 more
doaj   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

General Anaesthesia Versus Spinal Anaesthesia for Outpatient Total Hip and Knee Arthroplasty: A Randomised Trial Protocol

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction Same‐day discharge after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is increasing, but the optimal anaesthetic technique for outpatient pathways remains uncertain. Neuraxial anaesthesia is widely recommended based on observational evidence, whereas fast‐track programmes using short‐acting total ...
Erik Noppa, Karuna Dahlberg, Alex de Leon, Maziar Mohaddes, Anna Philipson, Peter Wildeman, Kristofer F. Nilsson   +6 more
wiley   +1 more source

Rare presentation of intrathecal morphine withdrawal psychosis

, 2017
We report a case of a 57-year-old male patient with intrathecal morphine pump failure who presented with psychosis as part of a clinical presentation of opioid withdrawal.
Rohit Aiyer, Boris Mekinulov, Semih Gungor, Anurag Bhatia, Vivek Jain   +4 more
core   +1 more source