International Journal of Molecular Sciences, 2014 The potential immune effects of titanium dioxide nanoparticles (nano-TiO2) are raising concern. Our previous study verified that nano-TiO2 induce local immune response in lung tissue followed by intratracheal instillation administration.
Yanyun Fu +8 more
semanticscholar +1 more source
Diosgenin ameliorates silica‐induced tuberculosis in rats
Animal Models and Experimental Medicine, EarlyView.Silicosis increases susceptibility to tuberculosis due to impaired macrophage function and oxidative stress. This study demonstrates that diosgenin, a steroidal saponin, significantly inhibits Mycobacterium smegmatis (IC₅₀ = 0.006 μg/mL), reduces lung fibrosis, and restores antioxidant enzyme levels (↑SOD, ↑CAT, ↓MDA) in silica‐exposed rats ...
Williams Asamoah Adu +5 more
wiley +1 more source
Inhaled Interleukin-10 before and after induction of experimental endotoxemia in the rat : effects on the inflammatory response [PDF]
, 2007 To determine the effects of inhaled IL-10 at different doses and different time points on the pulmonary and systemic inflammatory response during endotoxemia, 48 ventilated, anaesthetized rats (mean body weight ± standard deviation, 500 ± 33g) were ...
Nguyen, Ngoc-Thach
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Promising Prodiginins Biological Activities
Chemistry &Biodiversity, EarlyView.ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto +6 more
wiley +1 more source
Comparison of the Demonstration-Observation-Assistance-Performance Method and the Traditional Teaching Method for Endotracheal Intubation Skill Acquisition on a Simulator in Medical Students: An Educational Interventional Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Endotracheal Intubation (ETI) is the insertion of a breathing tube into the trachea—a critical, life-saving skill in Cardiopulmonary Resuscitation (CPR), both inside and outside the hospital setting.
Seni Potsangbam +2 more
doaj +1 more source
Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System
Journal of Visualized Experiments, 2014 Respiratory disease studies typically involve the use of murine models as surrogate systems. However, there are significant physiologic differences between the murine and human respiratory systems, especially in their upper respiratory tracts (URT).
M. Lawrenz +3 more
semanticscholar +1 more source
Comparing the effect of using normal saline, N-acetyl cysteine and not using them in endotracheal tube suction on physiologic parameters and the amount of secretions in intubated patients under mechanical ventilation [PDF]
, 2014 Aims: Today a large number of patients hospitalized in Intensive Care Unit need mechanical ventilation via an artificial air way. Since these patients have endotracheal tube, endotracheal suctioning is necessary for increasing oxygenation, cleaning the ...
Akbaryan Deheki, N. +6 more
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Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Developmental Dynamics, EarlyView.Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin +8 more
wiley +1 more source
Journal of Biophotonics, EarlyView.Partial liquid ventilation with oxygenized perfluorocarbon (PFC) is used to assess the limitations of imaging depth, caused by the refractive index mismatch between air and surfactants in the mouse lung. PFC does not help to overcome this limitation. Only removing scattering lipids and decolorization ex vivo, with tissue optical clearing, enhance the ...
Pascal Detampel +4 more
wiley +1 more source
Post Operative Severe Subcutaneous Emphysema
پزشکی بالینی ابن سینا, 2009 Introduction: Nowadays establishment of a safe and secure airway for general anesthesia is necessary and establishment of the airway , according to the anatomical and physiological state, may be accompanied with complications such as piriform sinus ...
Amir Asadi Fakhr +2 more
doaj