Results 141 to 150 of about 58,052 (292)

A Novel Bioabsorbable Covered Stent for Advancing Bile Duct Injury Management: A Preclinical Study in a Porcine Model (With Video)

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Self‐expandable metallic and plastic stents have been used for biliary tract injuries, but they are not entirely adequate as treatments. This study investigated the potential of our novel self‐expandable bioabsorbable covered stent (SEBCS) to treat bile duct injuries. We developed a novel SEBCS by covering a self‐expandable bioabsorbable stent
Mitsuo Miyazawa   +6 more
wiley   +1 more source

Landscape of Prophylactic Strategies Against Human Parainfluenza Virus Type 3

open access: yesReviews in Medical Virology, Volume 35, Issue 6, November 2025.
ABSTRACT Human parainfluenza virus‐type 3 (HPIV3) is a respiratory virus responsible for mild illnesses in most of the population and severe illnesses, such as bronchiolitis and pneumonia, in young children, immunocompromised individuals and the elderly.
Clémence Vacher   +4 more
wiley   +1 more source

Recollections of My Research in Developing the Heart-Lung Machine at Jefferson Medical College [PDF]

open access: yes, 2005
A personal memoir written by Dr. Bernard J. Miller about his introduction to and interest in medical research as well as his experiences working on the heart-lung machine. He focuses specifically on his working relationship with John H.
Miller, Bernard J.
core   +1 more source

Hesperetin Alleviates Bleomycin‐Induced Pulmonary Fibrosis by Modulating Cellular Senescence and Promoting Impaired Autophagy in a CISD2‐Dependent Manner

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
In bleomycin‐induced pulmonary fibrosis, CISD2 deficiency was associated with cellular senescence, oxidative stress, and impaired autophagy. Hesperetin, as a novel anti‐aging strategy, counteracts senescence and oxidative stress by restoring autophagy in a CISD2‐dependent manner.
Qi Lin   +4 more
wiley   +1 more source

Novel Humanized Mouse Model for Steroid‐Resistant Asthma

open access: yes
Allergy, EarlyView.
Shiho Yamada   +9 more
wiley   +1 more source

STAT6 Activation Exacerbates Ferroptosis in Airway Epithelium by Inhibiting PRKN‐Mediated Mitophagy in Pulmonary Fibrosis

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang   +7 more
wiley   +1 more source

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan   +17 more
wiley   +1 more source

Intratracheal Cuffs [PDF]

open access: bronze, 1969
S. G. HERSHEY   +3 more
openalex   +1 more source

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