Results 41 to 50 of about 76,026 (337)

Local pulmonary drug delivery in the preterm rabbit: feasibility and efficacy of daily intratracheal injections.

American Journal of Physiology - Lung cellular and Molecular Physiology, 2019
Recent clinical trials in newborns have successfully used surfactant as a drug carrier for an active compound, to minimize systemic exposure. To investigate the translational potential of surfactant-compound mixtures and other local therapeutics, a ...
Thomas Salaets, André Gie, J. Jiménez, Margo Aertgeerts, O. Gheysens, G. Vande Velde, M. Koole, X. Murgia, C. Casiraghi, Francesca Ricci, Fabrizio Salomone, G. Villetti, K. Allegaert, J. Deprest, J. Toelen   +14 more
semanticscholar   +1 more source

The practice of intensive care nurses using the closed suctioning system: An observational study

Iranian Journal of Nursing and Midwifery Research, 2015
Background: Endotracheal suctioning (ETS) is an essential procedure performed for mechanically ventilated patients. ETS can be either performed by open or closed suctioning system (CSS).
Somayeh Haghighat, AhmadReza Yazdannik
doaj   +1 more source

Experimental Pulmonary Granuloma Mimicking Sarcoidosis Induced by Propionibacterium acnes in Mice [PDF]

, 2010
Propionibacterium acnes has been implicated as an etiologic agent of sarcoidosis since the isolation of this bacterium from sarcoid lesions. We experimentally produced a murine pulmonary granuloma model using P.
Ichikawa, Hirohisa, Iio, Kouji, Iio, Tomoe Ueno, Kanehiro, Arihiko, Kataoka, Mikio, Miyahara, Nobuaki, Nakata, Yasunari, Okui, Yuhei, Tanimoto, Mitsune, Tanimoto, Yasushi   +9 more
core   +1 more source

Bleomycin Revisited: A Direct Comparison of the Intratracheal Micro-Spraying and the Oropharyngeal Aspiration Routes of Bleomycin Administration in Mice

Frontiers in Medicine, 2018
Idiopathic Pulmonary Fibrosis (IPF) is a fatal disease characterized by exuberant deposition of extracellular matrix components, deterioration of lung architecture and impairment of lung functions. Its etiopathogenesis remains incompletely understood, as
Ilianna Barbayianni, I. Ninou, A. Tzouvelekis, V. Aidinis   +3 more
semanticscholar   +1 more source

Awake supraglottic airway guided flexible bronchoscopic intubation in patients with anticipated difficult airways: a case series and narrative review [PDF]

Korean Journal of Anesthesiology, 2019
Awake intubation is indicated in difficult airways if attempts at securing the airway after induction of general anesthesia may lead to harm due to potential difficulties or failure in those attempts.
Wan Yen Lim, Patrick Wong
doaj   +1 more source

Novel alternative for submental intubation - A case report - [PDF]

Anesthesia and Pain Medicine, 2020
Background Submental intubation is commonly used during general anesthesia for maxillofacial surgeries as it provides a safe unrestricted surgical access compared to tracheostomy.
Inyoung Jung, Byung Hoon Yoo, Ji Youn Ju, Sijin Choi, Jun Heum Yon, Kye-Min Kim, Yun-Hee Lim, Woo Yong Lee   +7 more
doaj   +1 more source

Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation. [PDF]

, 2014
BackgroundSilver nanowires (Ag NWs) are increasingly being used to produce touchscreens for smart phones and computers. When applied in a thin film over a plastic substrate, Ag NWs create a transparent, highly-conductive network of fibers enabling the ...
Anderson, Donald S, Franzi, Lisa M, Gilbert, Benjamin, Pinkerton, Kent E, Saiki, Clare, Silva, Rona M, Van Winkle, Laura S, Vulpe, Chris D, Xu, Jingyi   +8 more
core   +1 more source

Oxidative DNA damage in the rat lung induced by intratracheal instillation and inhalation of nanoparticles

Journal of clinical biochemistry and nutrition, 2018
Nanoparticles are widely used as useful industrial materials. Therefore, their possible adverse health effects must be appraised. We assessed and compared the oxidative DNA damage caused by four different nanoparticles (TiO2, NiO, ZnO and CeO2).
Yun-Shan Li, Y. Ootsuyama, Y. Kawasaki, Y. Morimoto, T. Higashi, K. Kawai   +5 more
semanticscholar   +1 more source

Effects of adding dexmedetomidine to nebulized lidocaine on control of hemodynamic responses to laryngoscopy and intubation: A randomized clinical trial

Journal of Anaesthesiology Clinical Pharmacology, 2023
Background and Aims: Hemodynamic responses (HDR) to laryngoscopy and intubation are a significant concern for the anesthesiologist. This study aimed to compare the effects of intravenous Dexmedetomidine and nebulized Lidocaine for control of HDR to ...
Bhavna Sriramka, Zeeshan Haider Warsi, Janmejaya Sahoo   +2 more
doaj   +1 more source

The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma. [PDF]

, 2014
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously.
Anandan C., Arbes S. J., Asokananthan N., Billson J., Boyd M. J., Brown A., Brown A. D., Chan W. C., Chen J. C., Clive Robinson, Comoy E. E., David R. Garrod, Fattouh R., Gary K. Newton, Gelber L. E., Gough L., Jahnsen F. L., Jie Chen, Jihui Zhang, Jonathan P. Richardson, Kerry Jenkins, King C., Liu H., Marcaccini S., Mark R. Stewart, Meriel R. Major, Milan D. S., Moffatt M. F., Möller G. M., Nicola J. Francis-Newton, Peat J. K., Peat J. K., Pei Lai, Pichavant M., Platts-Mills T. A., Platts-Mills T. A., Platts-Mills T. A. E., Platts-Mills T. A. E., Prefontaine D., Purello-D’Ambrosia F., Rebekah E. Key, Robinson C., Silvestri M., Smith J. M., Sporik R., Squillace S. P., Steven M. Lloyd, Stewart G. A., Stuart Firth-Clark, Takai T., Trevor R. Perrior, Wan H., Ying S., Zhang J., Zhang J., Zhang J., Zhang J.   +56 more
core   +2 more sources