Results 51 to 60 of about 76,026 (337)

Evaluation of Pulmonary Toxicity of Zinc Oxide Nanoparticles Following Inhalation and Intratracheal Instillation

open access: yesInternational Journal of Molecular Sciences, 2016
We conducted inhalation and intratracheal instillation studies of zinc oxide (ZnO) nanoparticles in order to examine their pulmonary toxicity. F344 rats were received intratracheal instillation at 0.2 or 1 mg of ZnO nanoparticles with a primary diameter ...
Y. Morimoto   +14 more
semanticscholar   +1 more source

Hypoxia Preconditioning Increases Survival and Decreases Expression of Toll-like Receptor 4 in Pulmonary Artery Endothelial Cells Exposed to Lipopolysaccharide [PDF]

open access: yes, 2013
Pulmonary or systemic infections and hypoxemic respiratory failure are among the leading causes of admission to intensive care units, and these conditions frequently exist in sequence or in tandem.
Ali, Irshad   +7 more
core   +2 more sources

Usefulness of Intratracheal Instillation Studies for Estimating Nanoparticle-Induced Pulmonary Toxicity

open access: yesInternational Journal of Molecular Sciences, 2016
Inhalation studies are the gold standard for the estimation of the harmful effects of respirable chemical substances, while there is limited evidence of the harmful effects of chemical substances by intratracheal instillation.
Y. Morimoto   +5 more
semanticscholar   +1 more source

Respirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption

open access: yesDrug Delivery, 2017
Bosentan is an endothelin receptor antagonist (ERA) prescribed for patients with pulmonary arterial hypertension (PAH). The oral delivery of bosentan possesses several drawbacks such as low bioavailability (about 50%), short duration of action, frequent ...
Lydia A. Hanna   +2 more
doaj   +1 more source

Hyperangulated blades or direct epiglottis lifting to optimize glottis visualization in difficult Macintosh videolaryngoscopy: a non-inferiority analysis of a prospective observational study

open access: yesFrontiers in Medicine, 2023
PurposeIt is unknown if direct epiglottis lifting or conversion to hyperangulated videolaryngoscopes, or even direct epiglottis lifting with hyperangulated videolaryngoscopes, may optimize glottis visualization in situations where Macintosh ...
Viktor A. Wünsch   +9 more
doaj   +1 more source

The changes of endotracheal tube cuff pressure during manual and intermittent controlling in intensive care units

open access: yesIranian Journal of Nursing and Midwifery Research, 2020
Background: Usually, the endotracheal tube cuff pressure is controlled by cuff pressure monitoring. However, the intermittent pilot-manometer connection and disconnection may cause a change in the adjusted pressure.
Roghieh Nazari   +5 more
doaj   +1 more source

A fiberoptic orotracheal intubation successfully performed using a modified Guedel airway in a sedated emergency patient - A case report - [PDF]

open access: yesAnesthesia and Pain Medicine, 2020
Background Fiberoptic intubation is a powerful and safe technique to deal with airway difficulty, but it requires a lot of training to be able to perform correctly.
Jaeyoung Yang   +8 more
doaj   +1 more source

Pathogenesis of chronic obstructive pulmonary disease [PDF]

open access: yes, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +2 more sources

Multifunctional nanocarriers for lung drug delivery [PDF]

open access: yes, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
core   +2 more sources

Intratracheal insufflation of ether [PDF]

open access: yesTransactions of the Royal Academy of Medicine in Ireland, 1913
n ...
openaire   +2 more sources

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