Intratympanic treatment for tinnitus: A review
Since the 1940s, various attempts have been made to treat peripheral tinnitus by way of intratympanic injection. This administration procedure requires only low concentrations of medication, thanks to the highly targeted delivery to the site of action ...
Thomas Meyer
doaj +4 more sources
Intratympanic Therapies for Menière’s Disease [PDF]
There are multiple treatment options to consider when managing patients with Menière's disease. When conservative measures fail to control symptoms of Menière's disease, escalation of interventions may be required. Targeted drug delivery to the round window with intratympanic injections allows for local application of high concentrations of medications,
Matthew W. Miller, Yuri Agrawal
openalex +5 more sources
Systemic effects of intratympanic dexamethasone therapy [PDF]
ObjectiveThe study aimed to assess the possible systemic effects of intratympanic dexamethasone (IT-Dex) on the hypothalamic–pituitary–adrenal (HPA) axis, inflammation, and bone metabolism.DesignA prospective cohort study including 30 adult patients of a tertiary referral ENT clinic treated with 9.6 mg IT-Dex over a period of 10 days was carried out ...
Eva Nóvoa +2 more
openalex +3 more sources
Intratympanic Steroid for Menière's Disease: A Systematic Review [PDF]
Objectives: To investigate the beneficial effects and safety of intratympanic steroid installation compared with placebo in patients with Menière's disease. Methods: We performed a systematic literature search in MEDLINE and EMBASE for existing systematic reviews and individual ...
Louise Devantier +6 more
openalex +6 more sources
Effectiveness of Intratympanic Dexamethasone Injection for Tinnitus Treatment: A Systematic Review and Meta-Analysis [PDF]
Objectives Intratympanic dexamethasone injection (ITDI) has been introduced as a treatment option for subjective tinnitus. However, the effects of ITDI on patients with tinnitus remain unclear.
Juyong Chung +3 more
doaj +1 more source
Adjuvant Migraine Medications in the Treatment of Sudden Sensorineural Hearing Loss. [PDF]
Objectives/hypothesisTo examine the hearing outcomes of patients with sudden sensorineural hearing loss (SSNHL) treated with oral and intratympanic (IT) steroid only or a combination of steroid and migraine treatment.
Abouzari, Mehdi +7 more
core +1 more source
Intratympanic corticosteroids for Ménière’s disease
Ménière's disease is a condition that causes recurrent episodes of vertigo, associated with hearing loss and tinnitus. Corticosteroids are sometimes administered directly into the middle ear to treat this condition (through the tympanic membrane). The underlying cause of Ménière's disease is unknown, as is the way in which this treatment may work.
Webster, K +14 more
openaire +4 more sources
Intratympanic gentamicin for Ménière’s disease
Ménière's disease is a condition that causes recurrent episodes of vertigo, associated with hearing loss and tinnitus. Aminoglycosides are sometimes administered directly into the middle ear to treat this condition. The aim of this treatment is to partially or completely destroy the balance function of the affected ear.
Webster, Katie E +10 more
openaire +5 more sources
NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection. [PDF]
Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination.
Lee, Yoo Jin +5 more
core +10 more sources
Unilateral enlarged vestibular aqueduct syndrome and bilateral endolymphatic hydrops [PDF]
Enlarged vestibular aqueduct (EVA) syndrome is a common congenital inner ear malformation characterized by a vestibular aqueduct with a diameter larger than 1.5 mm, mixed or sensorineural hearing loss that ranges from mild to profound, and vestibular ...
NOLA, GIUSEPPE +3 more
core +7 more sources

