Results 41 to 50 of about 6,827 (229)

Intratympanic injection of dexamethasone for treatment of tinnitus in patients with sudden sensorineural hearing loss

open access: yesAudiology Research, 2012
The purpose of this study is to test the effectiveness of intratympanic dexamethasone injections as a treatment for severe tinnitus in idiopathic sudden sensorineural hearing loss (SNHL).
Tadao Yoshida   +4 more
doaj   +1 more source

The potential use of melatonin for preventing cisplatin ototoxicity : an insight for a clinical approach [PDF]

open access: yes, 2014
Cisplatin, one of the most effective and potent anticancer drugs, is used in the treatment of a wide variety of both pediatric and adult malignancies.
Araujo, Juliana Gusmão de   +3 more
core   +3 more sources

Hyperbaric Oxygen Therapy for Sudden Sensorineural Hearing Loss after Failure from Oral and Intratympanic Corticosteroid [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2012
Systemic and intratympanic steroids are most widely used for treating idiopathic sudden sensorineural hearing loss. Other treatments include vasodilator, immunosuppressant and antiviral medication. However, only 61% of patients achieve full recovery, and
Thanarath Imsuwansri   +2 more
doaj   +1 more source

Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2019
Introduction Oral steroids currently represent the standard treatment for idiopathic sudden sensorineural hearing loss The aim of this study is to assess the effectiveness of intratympanic dexamethasone injection for treating ‘Idiopathic sudden sensori ...
Rabi Hembrom   +4 more
doaj   +3 more sources

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

open access: yesFrontiers in Pharmacology
Introduction: One major obstacle in validating drugs for the treatment or prevention of hearing loss is the limited data available on the distribution and concentration of drugs in the human inner ear.
Adele Moatti   +18 more
doaj   +1 more source

Intratympanic dexamethasone for managing pregnant women with sudden hearing loss

open access: yesJournal of International Medical Research, 2019
Objective This study aimed to investigate the effect and safety of intratympanic dexamethasone in pregnant women with idiopathic sudden sensorineural hearing loss (ISSNHL).
Yaoyao Fu   +3 more
doaj   +1 more source

Inner Ear Therapeutics: An Overview of Middle Ear Delivery

open access: yesFrontiers in Cellular Neuroscience, 2019
There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel   +6 more
doaj   +1 more source

Local Delivery of Therapeutics to the Inner Ear: The State of the Science

open access: yesFrontiers in Cellular Neuroscience, 2019
Background: Advances in the understanding of the genetic and molecular etiologies of inner ear disorders have enabled the identification of therapeutic targets and innovative delivery approaches to the inner ear.
Caroline R. Anderson   +11 more
doaj   +1 more source

Sudden Sensorineural Hearing Loss: Results of intratympanic steroids as salvage treatment [PDF]

open access: yes, 2013
Objective: The aim of the present study was to verify the efficacy and the safety of intratympanic dexamethasone to treat sudden sensorineural hearing loss as salvage therapy. Materials and methods: A prospective study was conducted on patients affected
COSTANTINO, Claudio   +4 more
core   +1 more source

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