Results 51 to 60 of about 9,756 (290)
Intratympanic gentamicin treatment for Ménière's disease: A randomized, double-blind, placebo-controlled trial on dose efficacy - results of a prematurely ended study [PDF]
, 2014 Background: Gentamicin is used as a therapeutic agent for Ménière's disease because of its vestibulotoxicity causing chemo-ablation of the vestibular sensory epithelia. Its use has increased in recent years. However, there is still no consensus about the
Bremer, H.G. (Hendrik G.) +9 more
core +4 more sources
New possibilities in the treatment of Meniere's disease [PDF]
Vojnosanitetski Pregled, 2002 The results of the treatment of Meniere's disease by intratympanic instillation of gentamicin in 32 patients over a 24-months period were analyzed. The receded vestibular function was found in 96,8% patients whereas in the remaining 3,2% pronounced ...
Milanović Nada +3 more
doaj +1 more source
Journal of Otology, 2021 Objectives: To evaluate hearing outcome of salvage treatment with intratympanic steroids (ITS) in idiopathic sudden sensorineural hearing loss (ISSNHL) refractory to initial systemic steroid (SS) therapy.
Pedro Salvador +2 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 The treatment of acute hearing loss is clinically challenging due to the low efficacy of drug delivery into the inner ear. Local intratympanic administration of dexamethasone (D) and insulin-like growth factor 1 (IGF1) has been proposed for treatment ...
Jung-Ah Cho +5 more
semanticscholar +1 more source
Longitudinal Results With Intratympanic Dexamethasone in the Treatment of Ménière’s Disease [PDF]
, 2008 To assess patient satisfaction with vertigo control using intratympanic (IT) dexamethasone (12 mg/mL) for medically refractory unilateral Meniere's disease. STUDY DESIGN: Retrospective study.
Boleas-Aguirre, M.S. (María Soledad) +4 more
core +1 more source
A Case of Binocular Vertical Diplopia after Intratympanic Gentamicin Therapy
European Journal of Case Reports in Internal Medicine, 2019 Intratympanic gentamicin therapy is a useful alternative treatment for refractory Meniere's disease and is generally well tolerated. Visual disturbances as side effects of this treatment are rarely reported in the literature.
Giacomo Cioffi +4 more
doaj +1 more source
Efficiency of a dexamethasone nanosuspension as an intratympanic injection for acute hearing loss
Drug Delivery, 2021 Dexamethasone sodium phosphate (Dex-SP) is the most commonly used drug administered via intratympanic injection for the treatment of acute hearing loss, but its penetration efficiency into the inner ear is very low.
S. Jung +7 more
semanticscholar +1 more source
Round window membrane and delivery of biologically active agents into the cochlea [PDF]
, 2010 Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue.
Saber, Amanj K.
core +1 more source
JAMA Otolaryngology - Head and Neck Surgery, 2021 This randomized clinical trial compares levels of triamcinolone acetonide in perilymph and plasma after intratympanic injection.
V. Dahm +8 more
semanticscholar +1 more source
Journal of Otology, 2022 Background: Intratympanic administration of gadolinium chelate allows for a better visualization of endolymphatic hydrops (EH) using MRI than intravenous injection and was recently further improved to facilitate high-quality imaging of EH in 7 min.
Jing Zou +6 more
doaj +1 more source