Results 61 to 70 of about 6,412 (238)
Inner Ear Therapeutics: An Overview of Middle Ear Delivery
Frontiers in Cellular Neuroscience, 2019 There are a variety of methods to access the inner ear and many of these methods depend on utilizing the middle ear as a portal. In this approach the middle ear can be used as a passive receptacle, as part of an active drug delivery system, or simply as ...
Jaimin Patel +6 more
doaj +1 more source
Round window membrane and delivery of biologically active agents into the cochlea [PDF]
, 2010 Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue.
Saber, Amanj K.
core +1 more source
Advanced Science, EarlyView.The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li +12 more
wiley +1 more source
Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy: a randomized clinical study. [PDF]
, 2011 The aim of this study was to verify the efficacy and the safety of transtympanic dexamethasone to treat sudden sensorineural hearing loss as first and single drug method. Considering ethical implication of performing a mininvasive procedure on middle
AMODIO, Emanuele +6 more
core +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
A Novel 3D Printed Multi‐Material Simulator for Endoscopic Stapes Surgery: The “3D Stapes Trainer”
The Laryngoscope, EarlyView.The 3D Stapes Trainer represents a promising platform for training in endoscopic stapes surgery. This simulator consists of a multi‐use temporal bone holder and a single‐use middle ear box, printed with material Jetting 3D printing technology. Eight participants in a university ear surgery course used the simulator to perform endoscopic stapes surgery.
Giulia Molinari +8 more
wiley +1 more source
The blood labyrinthine barrier in the human normal and Meniere's disease macula utricle. [PDF]
, 2017 The ultrastructural organization of the blood labyrinthine barrier (BLB) was investigated in the human vestibular endorgan, the utricular macula, using postmortem specimens from individuals with documented normal auditory and vestibular function and ...
Ishiyama, Akira +4 more
core +2 more sources
Therapeutic Effect of Intratympanic Injection of Dexamethasone plus Hyaluronic Acid on Patients with Meniere's disease [PDF]
Iranian Journal of Otorhinolaryngology, 2019 Introduction: Intratympanic therapy, as a widely used treatment for inner ear diseases, is regarded as a therapeutic method in controlling the vertigo of the patients with Meniere’s disease.
Mehrdad Rogha +6 more
doaj +1 more source
Laryngoscope Investigative Otolaryngology, Volume 10, Issue 2, April 2025.ABSTRACT Objective To investigate the clinical characteristics and prognostic factors influencing treatment outcomes in pediatric sudden sensorineural hearing loss (PSSNHL). Methods A retrospective analysis was conducted on 63 children (64 ears) diagnosed with PSSNHL from January 2013 to December 2023.
Ranshi Zhao, Maoling Huang, Cheng Zhong
wiley +1 more source
The potential use of melatonin for preventing cisplatin ototoxicity : an insight for a clinical approach [PDF]
, 2014 Cisplatin, one of the most effective and potent anticancer drugs, is used in the treatment of a wide variety of both pediatric and adult malignancies.
Araujo, Juliana Gusmão de +3 more
core +3 more sources