Single and repeated-dose toxicity studies by intravaginal administration of <i>Lactobacillus plantarum</i> ATG-K2 powder in female rats. [PDF]
Toxicol ResKang JH +6 more
europepmc +4 more sources
Characterization of HPMC and PEG 400 Mucoadhesive Film Loaded with Retinyl Palmitate and Ketorolac for Intravaginal Administration. [PDF]
Int J Mol SciIntravaginal drug administration offers several advantages over other routes, primarily bypassing the initial stages of metabolism. Additionally, this route has demonstrated both local and systemic effects.
Hernández-González ME +6 more
europepmc +4 more sources
Enhancement of adaptive immunity to Neisseria gonorrhoeae by local intravaginal administration of microencapsulated interleukin 12. [PDF]
J Infect Dis, 2013 Liu Y, Egilmez NK, Russell MW.
europepmc +4 more sources
Intravaginal rings for continuous low-dose administration of cervical ripening agents [PDF]
International Journal of Pharmaceutics, 2018 Intravaginal rings (VRs) have been widely reported for administration of pharmaceutical drugs - most notably estrogens, progestogens and antiretrovirals - to the vagina for clinical benefit. Here, for the first time, we describe the design, manufacture and preclinical testing of VRs for sustained/controlled release of the cervical ripening agents ...
Wang, Yujing +3 more
openaire +5 more sources
Efficacy of Intravaginal Administration of Isosorbide Mononitrate Together with Misoprostol versus Misoprostol Alone in The Induction of Labor in Postdate Women [PDF]
The Egyptian Journal of Hospital Medicine, 2023 Background: Many studies proved that the administration of isosorbide mononitrate in combination with misoprostol might increase the success rates of abortion and delivery and help in the reduction of side effects of misoprostol.
Noha A. Sakna +3 more
openalex +2 more sources
TRENDS IN THE SCIENCES, 2023 Vulvovaginal candidiasis (VVC) is the most common fungal infection in the vaginal mucosa caused by an overgrowth of Candida albicans. The pathogenesis of C. albicans is determined by the presence of virulence secretory factors. Secreted Aspartyl Protease
Regina Ayu Fristiyanti +5 more
openalex +3 more sources
Intravaginal Administration of Fc-Fused IL7 Suppresses the Cervicovaginal Tumor by Recruiting HPV DNA Vaccine-Induced CD8 T Cells [PDF]
Clinical Cancer Research, 2016 Purpose: The induction of tissue-localized virus-specific CD8 T-cell response is essential for the development of an effective therapeutic vaccine against genital diseases, such as cervical cancer and genital herpes.
Choi, DH +9 more
core +2 more sources
International Journal of Reproductive BioMedicineBackground: Considering the considerable influence of the vaginal microbiome on endometrial receptivity and embryo implantation, we hypothesized that cases of recurrent implantation failure (RIF) might benefit from the intravaginal probiotic ...
Mina Naghi Jafarabadi +4 more
doaj +2 more sources
Abortion caused by intravaginal self-administration of Misoprostol: a case report
Romanian Journal of Legal Medicine, 2019 The authors present a case of a 38 years old woman, 21 weeks pregnant, that went to the emergency department, where she gave birth to a stillborn male fetus. A gynaecological examination revealed three partially dissolved tablets in the vagina. Chemical laboratory tests on the tablets showed they were Misoprostol (MP) tablets.
Martina Focardi +5 more
openaire +2 more sources
Intravaginal Administration Of Misoprostol Alone Versus Misoprostol And Isosorbidemononitrate For Cervical Ripening And Labour Induction [PDF]
, 2017 OBJECTIVES: To compare the efficacy and safety of intravaginal administration of misoprostol alone versus misoprostol and isosorbide mononitrate for cervical ripening and labour induction.
Nasreen Noor +3 more
openalex +2 more sources