Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury [PDF]
Frontiers in Pharmacology, 2019 Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins.
Alfonso Rubio-Navarro +2 more
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Frontiers in Immunology, 2018 Intravascular erythrocyte destruction, accompanied by the release of pro-oxidative and pro-inflammatory components hemoglobin and heme, is a common event in the pathogenesis of numerous diseases with heterogeneous etiology and clinical features.
Florence Gonnet +2 more
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Frontiers in Physiology, 2017 Intravascular hemolysis occurs in hereditary, acquired, and iatrogenic hemolytic conditions but it could be also a normal physiological process contributing to intercellular signaling. New evidence suggests that intravascular hemolysis and the associated
Ryszard Grygorczyk
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Therapeutics for sickle cell disease intravascular hemolysis [PDF]
Frontiers in PhysiologySickle cell disease (SCD) is a genetic disorder predominantly affecting individuals of African descent, with a significant global health burden. SCD is characterized by intravascular hemolysis, driven by the polymerization of mutated hemoglobin within ...
Jianyao Xue +4 more
doaj +6 more sources
Acute Intravascular Hemolysis and Methemoglobinemia Following Naphthalene Ball Poisoning
Indian Journal of Hematology and Blood Transfusion, 2014 Naphthalene (C10H8) is a natural component of fossil fuels such as petroleum, diesel and coal. The common consumer products made from naphthalene are moth repellents, in the form of mothballs or crystals, and toilet deodorant blocks.
Mayank Mishra, Rajan Kapoor, Mk Garg
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Severe Intravascular Hemolysis and Acute Kidney Injury Triggered by Mycoplasma-Associated Cold Agglutinin Disease: A Case Report [PDF]
Clinical Medicine Insights: Case ReportsIntroduction: Mycoplasma pneumoniae infection commonly causes mild respiratory illness, but cold agglutinin syndrome (CAS) is an uncommon extrapulmonary complication.
Ziad W. Elmezayen, Mohammad Adi
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Impact of intravascular hemolysis on functional and molecular alterations in the urinary bladder: implications for an overactive bladder in sickle cell disease [PDF]
Frontiers in PhysiologyPatients with sickle cell disease (SCD) display an overactive bladder (OAB). Intravascular hemolysis in SCD is associated with various severe SCD complications.
Tammyris Helena Rebecchi e Silveira +6 more
doaj +2 more sources
Case Report: First Case of Cefotaxime-Sulbactam-Induced Acute Intravascular Hemolysis in a Newborn With ABO Blood Type Incompatibility by the Mechanism of Non-Immunologic Protein Adsorption [PDF]
Frontiers in Immunology, 2021 BackgroundABO blood type incompatibility hemolytic disease of newborn (ABO-HDN) and drug-induced immune hemolytic anemia (DIIHA) due to non-immunologic protein adsorption (NIPA) mainly cause extravascular hemolysis.
Yuanjun Wu +7 more
doaj +2 more sources
A Case Report of Intravascular Hemolysis and Heme Pigment–Induced Nephropathy Following AngioJet Thrombectomy for Thrombosed DIPS Shunt [PDF]
Canadian Journal of Kidney Health and Disease, 2020 Rationale: The AngioJet system is a combined mechanical and pharmacological device used for thrombectomy. As a result of the mechanical disruption of clot, intravascular hemolysis is noted to occur. Rarely, intravascular hemolysis can be severe enough to
Si Tian, Nicolette Sinclair, Sachin Shah
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Infection and Drug Resistance, 2022 Zhiqi Li,1 Chongbing Yan,2 Xiaohui Gong,2 Junfang Wang2 1Department of Neonatology, ChangNing Maternity and Infant Health Institute, Shanghai, 200051, People’s Republic of China; 2Department of Neonatology, Shanghai Children’s Hospital, Shanghai Jiao ...
Junfang Wang, Xiaohui Gong
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