Results 41 to 50 of about 770,426 (212)

Acute Alteration of Plasma Renin Activity by Large Doses of Intravenous Prednisolone [PDF]

, 1972
Large doses of intravenous glucocorticoids have been used in an attempt to reverse homograft rejection. The intravenous administration of 1 g prednisolone over 1 hr resulted in a significant acute reduction of plasma renin activity in 5 normal subjects ...
Halgrimson, CG, Katz, FH, Pinggera, WF, Popovtzer, MM, Starzl, TE   +4 more
core   +1 more source

Short-Term Intravenous Administration of Carbon Nano-Onions is Non-Toxic in Female Mice

International Journal of Nanomedicine, 2023
Yi Zhen Tan,1 Lucy R Thomsen,1 Nensi Shrestha,1 Adalberto Camisasca,2 Silvia Giordani,2 Rhonda Rosengren1 1Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9016, New Zealand; 2School of Chemical Sciences, Dublin City University ...
Tan YZ, Thomsen LR, Shrestha N, Camisasca A, Giordani S, Rosengren R   +5 more
doaj  

Native Study of the Behaviour of Magnetite Nanoparticles for Hyperthermia Treatment during the Initial Moments of Intravenous Administration

Pharmaceutics, 2022
Magnetic nanoparticles (MNPs) present outstanding properties making them suitable as therapeutic agents for hyperthermia treatments. Since the main safety concerns of MNPs are represented by their inherent instability in a biological medium, strategies ...
Valentina Marassi, Ilaria Zanoni, Simona Ortelli, Stefano Giordani, Pierluigi Reschiglian, Barbara Roda, Andrea Zattoni, Costanza Ravagli, Laura Cappiello, Giovanni Baldi, Anna L. Costa, Magda Blosi   +11 more
doaj   +1 more source

Pharmacokinetics of Mebudipine, a new calcium antagonist, following single intravenous and oral administrations in rats [PDF]

The pharmacokinetics of a new calcium antagonist, mebudipine, was studied after a single intravenous (0.5mg/kg) and oral (10mg/kg) administration to rats.
بهلولی, شهاب, محمودیان, مسعود, کیهانفر, فریبرز   +2 more
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Intravenous and Oral Paracetamol Have the Same Effect in Reducing Fever in Pediatric Patients

MCBS (Molecular and Cellular Biomedical Sciences), 2020
Background: The antipyretic effect of intravenous versus oral paracetamol is not well known. This study was aimed to compare the antipyretic effect of intravenous and oral paracetamol therapy to reduce fever.
Fitri Asymida, Yazid Dimyati, Bidasari Lubis, Aznan Lelo, Muhammad Ali, Ayodhia Pitaloka Pasaribu, Syahril Pasaribu   +6 more
doaj   +1 more source

Evaluation of the Neutralizing Antibody STE90-C11 against SARS-CoV-2 Delta Infection and Its Recognition of Other Variants of Concerns

Viruses, 2023
As of now, the COVID-19 pandemic has spread to over 770 million confirmed cases and caused approximately 7 million deaths. While several vaccines and monoclonal antibodies (mAb) have been developed and deployed, natural selection against immune ...
Leila Abassi, Federico Bertoglio, Željka Mačak Šafranko, Thomas Schirrmann, Marina Greweling-Pils, Oliver Seifert, Fawad Khan, Maeva Katzmarzyk, Henning Jacobsen, Natascha Gödecke, Philip Alexander Heine, André Frenzel, Helena Nowack, Stefan Dübel, Ivan-Christian Kurolt, Roland E. Kontermann, Alemka Markotić, Maren Schubert, Michael Hust, Luka Čičin-Šain   +19 more
doaj   +1 more source

Targeting capacity, safety and efficacy of engineered extracellular vesicles delivered by transdermal microneedles to treat plasmacytoma in mice

Clinical and Translational Medicine
Background Engineered extracellular vesicles (EVs) are emerging as a highly potential platform for targeted drug delivery in cancer therapy. Although intravenous injection is commonly used in EV treatment, there is growing interest in using microneedles (
Yulin Cao, Xuan Hu, Di Wu, Yuxuan Jiang, Yali Yu, Shan Wang, Wenlan Chen, Yaoying Long, Liuyue Xu, Jiao Qu, Bianlei Yang, Blal Chakhabi, Hongxiang Wang, Yong Deng, Lei Chen, Zhichao Chen, Qiubai Li   +16 more
doaj   +1 more source

Effects of Particle Size of Curcumin Solid Dispersions on Bioavailability and Anti-Inflammatory Activities

Antioxidants, 2023
The delivery of curcumin (CUR) using the solid dispersion system (CUR solid dispersions; C-SDs) has been shown to improve CUR bioavailability. However, it is unclear how different particle sizes of C-SDs affect the bioavailability and biological ...
Chihiro Kato, Mayuko Itaya-Takahashi, Taiki Miyazawa, Junya Ito, Isabella Supardi Parida, Hiroki Yamada, Akari Abe, Mika Shibata, Keita Someya, Kiyotaka Nakagawa   +9 more
doaj   +1 more source

Intravenous Voriconazole after Toxic Oral Administration [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not.
Alffenaar, J.W.C., Van Assen, S., De Monchy, J.G.R., Uges, D.R.A., Kosterink, J.G.W., Van Der Werf, T.S.   +5 more
openaire   +2 more sources

Delivery of the vitamin E compound tocotrienol to cancer cells [PDF]

, 2011
Tocotrienol, a member of the vitamin E family of compounds, is currently receiving increased attention because of its highly promising anti-cancer effects.
Dufès, Christine
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