Results 181 to 190 of about 3,280,417 (245)

Doxorubicin‐induced Cardiotoxicity in Dogs: A Narrative Review

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Doxorubicin, an anthracycline widely used in both human and veterinary oncology, is highly effective against a variety of malignancies in dogs, including lymphomas, sarcomas and carcinomas. Despite its efficacy, doxorubicin exposure can be associated with cardiotoxicity, which may present acutely or chronically, potentially leading to severe ...
Supita Sunpongsri   +4 more
wiley   +1 more source

Dexmedetomidine as an Adjuvant for Intravenous Regional Anesthesia in Upper Limb Surgeries.

open access: yesAnesth Essays Res, 2017
Subramanya V   +3 more
europepmc   +1 more source

Temporary caval occlusion technique during right divisional hepatectomy for massive hepatocellular carcinoma with caudal vena cava compression/involvement in dogs

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To describe the perioperative and long‐term outcomes of dogs with massive hepatocellular carcinoma (HCC) in the right hepatic division causing compression or involvement of the caudal vena cava (CVC) treated with right divisional hepatectomy using temporary caval occlusion (TCO). Study design Retrospective case series.
Kumiko Ishigaki   +6 more
wiley   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Cerebral oxygen extraction across different exercise intensities: Role of arterial PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$

open access: yesExperimental Physiology, EarlyView.
Abstract Stability in cerebral oxygen extraction fraction (OEF) is typically determined by alterations in cerebral blood flow (CBF). At rest, arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$) and OEF exhibit a strong inverse relationship owing to the powerful influence of PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_2}}}$
L. Madden Brewster   +11 more
wiley   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana   +2 more
wiley   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid   +17 more
wiley   +1 more source

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