Results 121 to 130 of about 51,241 (251)

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, Volume 13, Issue 13, 3 March 2026.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Longitudinal plasma interleukin‐6 and post‐stroke cognitive outcomes: The Stroke‐IMPaCT study

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Inflammatory factors, particularly interleukin (IL)‐6, are implicated in post‐stroke cognitive decline, yet the association with longitudinal changes in these markers remains unclear. METHODS Plasma IL‐6 and other inflammatory markers were measured within 96 hours of ischemic stroke, and at 6–9 and 18–21 months, alongside ...
Natasha S. Carmichael, Harry R. Deijnen, Siew Yan Wong, Thomas O. Williams, Evangelos Kontopantelis, Luke Cowie, Eileen Jones, Lauren Drag, Marion S. Buckwalter, John R. Grainger, Stuart M. Allan, Craig J. Smith   +11 more
wiley   +1 more source

Clinical and epidemiological overview of hyperacute ischemic stroke patients treated with intravenous thrombolysis

The Egyptian Journal of Internal Medicine
Background Hyperacute ischemic stroke is a type of ischemic stroke that occurs rapidly and suddenly due to blockage of blood flow to the brain, with onset within 0–24 h.
Lisda Amalia, Putri Qonitah
doaj   +1 more source

Intravenous thrombolysis for acute stroke.

Cleveland Clinic Journal of Medicine, 2004
Intravenous t-PA is effective if given to appropriate patients within 3 hours of stroke onset, and its effectiveness increases even within the first 3 hours when given as soon as possible. t-PA is reasonably safe if used in a carefully defined manner that ensures close attention to blood pressure, careful patient monitoring, no use of heparin and ...
openaire   +2 more sources

Tenecteplase Versus Alteplase for First‐Pass Reperfusion in Basilar Artery Occlusion Stroke Thrombectomy

Annals of Neurology, Volume 99, Issue 3, Page 692-704, March 2026.
Objective The first‐pass effect (FPE), defined as excellent reperfusion after a single attempt, is associated with improved outcomes in large vessel occlusion stroke. We evaluated whether intravenous tenecteplase (TNK) compared with alteplase (TPA) increases the likelihood of FPE in basilar artery occlusion (BAO).
Dylan N. Wolman, Rahul R. Karamchandani, Sina Hemmer, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Clemens M. Schirmer, Alexandra R. Paul, Bradley N. Bohnstedt, Raul G. Nogueira, Philipp Hendrix   +38 more
wiley   +1 more source

Stroke Severity Affects Timing: Time From Stroke Code Activation to Initial Imaging is Longer in Patients With Milder Strokes. [PDF]

, 2018
Optimizing the time it takes to get a potential stroke patient to imaging is essential in a rapid stroke response. At our hospital, door-to-imaging time is comprised of 2 time periods: the time before a stroke is recognized, followed by the period after ...
Dhamoon, Mandip, Kwei, Kimberly T., Liang, John W., Tuhrim, Stanley, Wilson, Natalie   +4 more
core   +1 more source

Revisiting Incomplete Tissue‐Level Reperfusion Following Successful Thrombectomy for Acute Ischemic Stroke

Annals of Neurology, Volume 99, Issue 3, Page 668-683, March 2026.
[Color figure can be viewed at www.annalsofneurology.org] Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains ...
Yue Qiao, Adrien Ter Schiphorst, Yi Xu, Jean‐Claude Baron, Wenbo Zhao   +4 more
wiley   +1 more source

Prospective Open‐Label Safety Study of Edaravone Dexborneol in Filipino Patients With Acute Ischemic Stroke

Brain and Behavior, Volume 16, Issue 3, March 2026.
This prospective, single‐arm study evaluated the real‐world safety of edaravone dexborneol in Filipino patients with acute ischemic stroke treated within 48 h of symptom onset. Adverse events were predominantly mild and transient, with headache and reversible liver enzyme elevations being the most common. No treatment discontinuations, life‐threatening
Zenyros Faith Sabellano, Bonifacio Pedregosa II, Laurence Kristoffer Batino, Jose Navarro   +3 more
wiley   +1 more source

Coronary Slow Flow and No‐Reflow During Percutaneous Coronary Intervention: Contemporary Insights Into Imaging‐Guided Prediction, Prevention, and Management

Catheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 1198-1205, March 1, 2026.
ABSTRACT Coronary slow flow (SF) and no‐reflow (NR) are clinically significant complications of percutaneous coronary intervention (PCI), particularly in ST‐segment elevation myocardial infarction (STEMI) and saphenous vein graft (SVG) interventions. Angiographically defined as impaired myocardial perfusion despite restored epicardial patency, SF/NR ...
Bharat Khialani, Eran Sim, George Touma, Sarah Fairley, Cuneyt Ada, Bernard Wong   +5 more
wiley   +1 more source

From Thrombolysis to Transplant: Navigating the Storm of Delayed STEMI and Cardiogenic Shock

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Delayed STEMI presentation can cause extensive myocardial necrosis, left ventricular thrombus, cardiogenic shock, and progression to end‐stage heart failure despite reperfusion. Early recognition and timely transfer to specialized shock centers are critical.
Syed Rafay Hussain Zaidi, Muhammad Sheraz Hameed, Muhammad Ahsan, Hamza Ishfaq, Ali Iqbal, Azka Mirza, Sadia Rekhum, Muhammad Sohaib Alvi, Muhammad Usama Naveed   +8 more
wiley   +1 more source