Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]
<p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly.
Bluhmki, E.+4 more
core +1 more source
Background: N-terminal pro-brain natriuretic peptide (NT-proBNP) levels are a promising biomarker for predicting stroke outcomes; however, their prognostic validity is not well-understood in patients who have undergone intravenous thrombolysis.
Ke-Jia Zhang+11 more
doaj +1 more source
Development of a decision analytic model to support decision making and risk communication about thrombolytic treatment [PDF]
Background Individualised prediction of outcomes can support clinical and shared decision making. This paper describes the building of such a model to predict outcomes with and without intravenous thrombolysis treatment following ischaemic stroke ...
A Bannat+7 more
core +2 more sources
Recanalization of extracranial internal carotid artery occlusion after i.v. thrombolysis for acute ischemic stroke. [PDF]
BACKGROUND: Although extracranial internal carotid artery (e-ICA) occlusion is a common pathology in patients undergoing intravenous thrombolysis for treatment of acute ischemic stroke, no data on e-ICA recanalization rate or potential effects on outcome
Raimund Pechlaner+6 more
doaj +1 more source
"Sudden Drop" in Blood Pressure is Associated With Recanalization After Thrombolysis. [PDF]
We aim to investigate whether the phenomenon of "sudden drop" in blood pressure (BP) within the first 2 hours is associated with vessel recanalization.We retrospectively examined clinical and imaging data from a consecutive series of patients with stroke
Cao, Jin+4 more
core +1 more source
Experience in using intravenous thrombolysis in ischemic stroke in Tatarstan
The paper describes experience with intravenous thrombolysis used in a few vascular centers of the Republic of Tatarstan in the past 5 years. Intravenous thrombolysis with alteplase (actilise) was carried in 300 patients (188 men and 112 women) aged 21 ...
D. R. Khasanova, T. V. Demin
doaj +1 more source
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B.+8 more
core +1 more source
We report a case of intravenous thrombolysis in acute ischemic stroke of anterior choroidal artery following the antagonization of dabigatran with idarucizumab.
Maren Hieber, Juergen Bardutzky
doaj +1 more source
Objectives: Intravenous thrombolysis alone has poor recanalization rates in large vessel occlusion strokes. Bridging thrombolysis has evolved as a standard treatment approach in emergent large vessel occlusions.
Chintan Prajapati+4 more
doaj +1 more source
Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent+28 more
core +5 more sources