Results 51 to 60 of about 53,924 (268)

Intravenous thrombolysis for acute stroke. [PDF]

Cleveland Clinic Journal of Medicine, 2004
Intravenous t-PA is effective if given to appropriate patients within 3 hours of stroke onset, and its effectiveness increases even within the first 3 hours when given as soon as possible. t-PA is reasonably safe if used in a carefully defined manner that ensures close attention to blood pressure, careful patient monitoring, no use of heparin and ...
openaire   +2 more sources

Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset [PDF]

, 2010
<p><b>Background and Purpose:</b> Antiplatelets (APs) may increase the risk of symptomatic intracerebral hemorrhage (ICH) following intravenous thrombolysis after ischemic stroke.</p> <p><b>Methods:</b> We ...
Ahmed, N., Diedler, J., Ford, G.A., Lees, K.R., Luijckx, G.J., Overgaard, K., Ringleb, P., Soinne, L., Sykora, M., Uyttenboogaart, M., Wahlgren, N.   +10 more
core   +7 more sources

Predictive value of monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) for poor prognosis after intravenous thrombolytic therapy for acute ischaemic stroke

Archives of Medical Science
Introduction The purpose of this study was to examine the relationship between monocyte-to-high-density lipoprotein-cholesterol ratio (MHR) and poor short-term 3-month and long-term 6-month prognosis after intravenous thrombolysis in patients with acute ...
Yinglei Li, Lingyun Xi, Litao Li
doaj   +1 more source

Determinants of 1-Year Unfavorable Outcomes of Intravenous Alteplase Thrombolysis for Acute Ischemic Stroke

Clinical and Applied Thrombosis/Hemostasis, 2023
Objective Intravenous thrombolytic therapy has become the standard of treatment for eligible patients with ischemic stroke. However, outcomes after receiving intravenous thrombolytic therapy vary widely.
Mingfeng Zhai MD, Jinwei Yang MD, Xiaoyan Cao MD, Yingying Li MD, Hui Xu MD, Yu Wang MD   +5 more
doaj   +1 more source

Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]

, 2007
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R., Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +4 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Intravenous thrombolysis for acute ischemic stroke

Diagnostic and Interventional Imaging, 2014
Intravenous thrombolysis (IVT) with alteplase remains the standard treatment for acute ischemic stroke. Although IVT can be started up to 4.5 hours after symptoms' onset, it is all the more effective and safe when started early. It allows a 10% absolute reduction in the risk of handicap or death at 3 months, despite a 2-7% risk of symptomatic ...
Guillaume Turc, Guillaume Turc, David Calvet, David Calvet, Clothilde Isabel   +4 more
openaire   +3 more sources

Intravenous Thrombolysis in a Stroke Patient Receiving Rivaroxaban [PDF]

Cerebrovascular Diseases Extra, 2013
Rivaroxaban, a novel direct factor Xa inhibitor with consistent anticoagulant properties, was found to be safer and equally effective as warfarin in the prevention of embolic stroke in patients with nonvalvular atrial fibrillation [1, 2] . Effective anticoagulation predisposes to bleeding and represents a contraindication for intravenous thrombolysis ...
Fluri, Felix, Heinen, Florian, Kleinschnitz, Christoph   +2 more
openaire   +5 more sources

Intravenous thrombolysis for acute ischemic stroke in centenarians

European Geriatric Medicine, 2021
The benefit of intravenous alteplase is well established for patients with disabling stroke symptoms regardless of age, although data on outcomes in centenarian patients are scarce. We present our experience in patients beyond 100 years.Descriptive study including centenarians from our single-centre prospective registry who underwent intravenous ...
A Sánchez Sánchez, J. Masjuan Vallejo, J. Masjuan Vallejo, A. de Felipe Mimbrera, R. Sainz Amo, Sebastián García-Madrona, Sebastián García-Madrona, M C Matute Lozano, A. Cruz Culebras, J. Gómez Corral, B. Baena Alvarez, F Rodríguez Jorge, R. Vera Lechuga   +12 more
openaire   +4 more sources

Response by Bivard et al to letter regarding article, "Impact of Computed Tomography Perfusion Imaging on the Response to Tenecteplase in Ischemic Stroke: Analysis of 2 Randomized Controlled Trials" [PDF]

, 2017
No abstract ...
Bivard, Andrew, Muir, Keith, Parsons, Mark   +2 more
core   +1 more source