Results 111 to 120 of about 373,665 (256)

Pharmacokinetic data support 6-hourly dosing of intravenous vitamin C to critically ill patients with septic shock.

Critical Care and Resuscitation, 2019
OBJECTIVES To study vitamin C pharmacokinetics in septic shock. DESIGN Prospective pharmacokinetic study. SETTING Two intensive care units. PARTICIPANTS Twenty-one patients with septic shock enrolled in a randomised trial of high dose vitamin C ...
Elizabeth P Hudson, J. Collie, T. Fujii, N. Luethi, A. Udy, Sarah Doherty, G. Eastwood, Fumitaka Yanase, T. Naorungroj, L. Bitker, Y. Abdelhamid, R. Greaves, A. Deane, R. Bellomo   +13 more
semanticscholar   +1 more source

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, EarlyView.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Intravenous vitamin C as adjunctive therapy for enterovirus/rhinovirus induced acute respiratory distress syndrome

World Journal of Critical Care Medicine, 2017
We report a case of virus-induced acute respiratory distress syndrome (ARDS) treated with parenteral vitamin C in a patient testing positive for enterovirus/rhinovirus on viral screening.
Alpha A Fowler III, Christin Kim, L. Lepler, R. Malhotra, Orlando Debesa, R. Natarajan, B. Fisher, A. Syed, C. DeWilde, Anna G. Priday, V. Kasirajan   +10 more
semanticscholar   +1 more source

Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy

Equine Veterinary Journal, EarlyView.
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan, Blythe Durbin‐Johnson, Kevin Woolard, Andrew D. Miller, Carrie J. Finno   +4 more
wiley   +1 more source

Fructose-1,6-diphosphate and vitamin C combination increases seizure threshold in chemical kindling models

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Fructose-1,6-diphosphate (FDP), through its activity in glucose metabolism, has anticonvulsant efficacy whereas vitamin C acts as neuromodulator.
Bela Paras Samariya, Gaurang B Shah
doaj   +1 more source

Limb Compression Therapy and Chemotherapy‐Induced Peripheral Neuropathy in Women With Gynecologic Cancers: A Prospective Self‐Controlled Study(NEURO‐GLOVE Trial)

International Journal of Cancer, EarlyView.
With no effective drug‐based prevention strategies available for chemotherapy‐induced peripheral neuropathy (CIPN), research in neuroprotective approaches has grown. Of particular interest is mechanical compression, which may protect nerves by temporarily reducing blood flow during treatment. The authors here conducted a prospective trial in women with
Kadriye Başkurt, Galip Can Uyar, Enes Yeşilbaş, Fatma Zehra Altunç, Damla Erimhan Çevik, İsmet Murat Melek, Yasemin Eren, Ömür Berna Çakmak Öksüzoğlu, Kadriye Bir Yücel, Antonio Di Meglio, Isabelle Ray‐Coquard, Osman Sütcüoğlu   +11 more
wiley   +1 more source

Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury

Critical Care, 2018
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2018.
Angelique M. E. Spoelstra-de Man, Paul W. G. Elbers, Heleen M. Oudemans-van Straaten   +2 more
doaj   +1 more source

Hyperemesis gravidarum and oral health: A scoping review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy (NVP), associated with dehydration, nutritional deficiencies, and systemic complications. Although recurrent vomiting, altered dietary patterns, and medication effects might plausibly affect oral health, this relationship has not been comprehensively ...
Niamh Coffey, Lucy James, Angela C. Flynn, Zeinab El‐Dirani, Shahnawaz Khijmatgar   +4 more
wiley   +1 more source

Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome

Case Reports in Critical Care, 2016
This case report summarizes the first use of intravenous vitamin C employed as an adjunctive interventional agent in the therapy of recurrent acute respiratory distress syndrome (ARDS).
Amit Bharara, Catherine Grossman, Daniel Grinnan, Aamer Syed, Bernard Fisher, Christine DeWilde, Ramesh Natarajan, Alpha A. (Berry) Fowler   +7 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source