Antioxidants, 2023 Community-acquired pneumonia (CAP) is characterized by elevated markers of inflammation and oxidative stress and depleted circulating concentrations of the antioxidant nutrient vitamin C.
Emma Vlasiuk +2 more
exaly +6 more sources
The effectiveness of high-dose intravenous vitamin C for patients with coronavirus disease 2019: A systematic review and meta-analysis [PDF]
Complementary Therapies in Medicine, 2022 Objectives: Vitamin C has anti-inflammatory effects. This review aimed to investigate the therapeutic effect of high-dose intravenous vitamin C (HDIVC) in patients with coronavirus disease 2019 (COVID-19). Methods: The following key phrases were searched
Yoo Jin Choo +2 more
exaly +4 more sources
The Use of Intravenous Vitamin C as a Supportive Therapy for a Patient with Glioblastoma Multiforme [PDF]
Antioxidants, 2018 Glioblastoma multiforme is a high grade malignant brain tumour with a poor prognosis. Here we report the case of a woman with glioblastoma who lived for over four years from diagnosis (median survival 12 months and 2% survival for three years ...
Anitra Carr
exaly +5 more sources
Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial [PDF]
Critical Care, 2022 Background Intravenous vitamin C administration in septic shock may have a sparing effect on vasopressor requirements, and vitamin C’s enzyme cofactor functions provide a mechanistic rationale.
Patrice Rosengrave +9 more
doaj +2 more sources
Pharmacokinetic Evaluation of Intravenous Vitamin C: A Classic Pharmacokinetic Study. [PDF]
Clin Pharmacokinet, 2022 Intravenous vitamin C (IVC) is used in a variety of disorders with limited supporting pharmacokinetic data. Herein we report a pharmacokinetic study in healthy volunteers and cancer participants with IVC doses in the range of 1-100 g.A pharmacokinetic study was conducted in 21 healthy volunteers and 12 oncology participants.
Chen P +11 more
europepmc +3 more sources
Intravenous vitamin C as micronutrient therapy in patients with sepsis or septic shock: an updated systematic review and meta-analysis of randomized controlled trials [PDF]
Frontiers in NutritionObjectiveThe adjunctive therapeutic value of vitamin C in sepsis or septic shock patients remains controversial. This study aimed to evaluate the therapeutic efficacy and safety of intravenous administration of vitamin C in sepsis or septic shock ...
Binrong Cai +15 more
doaj +2 more sources
Effect of perioperative single dose intravenous vitamin C on pain after total hip arthroplasty [PDF]
Journal of Orthopaedic Surgery and ResearchIntroduction Vitamin c can relieve the pain after other diseases, but there are no studies on whether vitamin C can relieve the pain after hip replacement.
Guangtao Han +4 more
doaj +2 more sources
Is intravenous vitamin C contraindicated in patients with G6PD deficiency? [PDF]
Critical Care, 2019 Paul E. Marik
doaj +5 more sources
Nutrition and Metabolic Insights, 2016 Intravenous administration of vitamin C has been shown to decrease oxidative stress and, in some instances, improve physiological function in adult humans.
Janelle L. Davis +8 more
doaj +2 more sources
Case report: The efficacy of adding high doses of intravenous vitamin C to the combination therapy of atezolizumab and bevacizumab in unresectable HCC [PDF]
Frontiers in MedicineIntroductionVitamin C (L-ascorbic acid) plays a vital role in human physiology, serving as both an antioxidant and a cofactor in enzymatic reactions. High-dose intravenous Vitamin C can achieve significantly elevated plasma concentrations, potentially ...
Waleed Kian +7 more
doaj +2 more sources