Results 1 to 10 of about 373,665 (256)

The effectiveness of high-dose intravenous vitamin C for patients with coronavirus disease 2019: A systematic review and meta-analysis [PDF]

Complementary Therapies in Medicine, 2022
Objectives: Vitamin C has anti-inflammatory effects. This review aimed to investigate the therapeutic effect of high-dose intravenous vitamin C (HDIVC) in patients with coronavirus disease 2019 (COVID-19). Methods: The following key phrases were searched
Sang Gyu Kwak, Yoo Jin Choo, Min Cheol Chang   +2 more
doaj   +5 more sources

Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial [PDF]

Critical Care, 2022
Background Intravenous vitamin C administration in septic shock may have a sparing effect on vasopressor requirements, and vitamin C’s enzyme cofactor functions provide a mechanistic rationale.
Patrice Rosengrave, Emma Spencer, Jonathan Williman, Jan Mehrtens, Stacey Morgan, Tara Doyle, Kymbalee Van Der Heyden, Anna Morris, Geoff Shaw, Anitra C. Carr   +9 more
doaj   +3 more sources

Pharmacokinetic Evaluation of Intravenous Vitamin C: A Classic Pharmacokinetic Study. [PDF]

Clin Pharmacokinet, 2022
Intravenous vitamin C (IVC) is used in a variety of disorders with limited supporting pharmacokinetic data. Herein we report a pharmacokinetic study in healthy volunteers and cancer participants with IVC doses in the range of 1–100 g.
Chen P, Reed G, Jiang J, Wang Y, Sunega J, Dong R, Ma Y, Esparham A, Ferrell R, Levine M, Drisko J, Chen Q.   +11 more
europepmc   +4 more sources

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials. [PDF]

JAMA, 2023
Importance The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain. Objective To determine whether vitamin C improves outcomes for patients with COVID-19.
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Horvat C, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F.   +85 more
europepmc   +7 more sources

Effect of perioperative single dose intravenous vitamin C on pain after total hip arthroplasty [PDF]

Journal of Orthopaedic Surgery and Research
Introduction Vitamin c can relieve the pain after other diseases, but there are no studies on whether vitamin C can relieve the pain after hip replacement.
Guangtao Han, Yanfeng Gan, Qin Wang, Shuo Sun, Pengde Kang   +4 more
doaj   +3 more sources

Intravenous Vitamin C in Adults with Sepsis in the Intensive Care Unit

New England Journal of Medicine, 2022
BACKGROUND Studies that have evaluated the use of intravenous vitamin C in adults with sepsis who were receiving vasopressor therapy in the intensive care unit (ICU) have shown mixed results with respect to the risk of death and organ dysfunction ...
Jason Shahin, Djillali Annane, Michael Chasse   +2 more
exaly   +5 more sources

Low Vitamin C Concentrations in Patients with Community-Acquired Pneumonia Resolved with Pragmatic Administration of Intravenous and Oral Vitamin C

Antioxidants, 2023
Community-acquired pneumonia (CAP) is characterized by elevated markers of inflammation and oxidative stress and depleted circulating concentrations of the antioxidant nutrient vitamin C.
Anitra C. Carr, Emma Vlasiuk, Masuma Zawari, Amy Scott-Thomas, Malina Storer, Michael Maze, Stephen T. Chambers   +6 more
doaj   +5 more sources

Efficacy of intravenous vitamin C in management of moderate and severe COVID-19: A double blind randomized placebo controlled trial [PDF]

Journal of Family Medicine and Primary Care, 2022
Aim: To study the efficacy of intravenous vitamin C in management of moderate and severe COVID-19. Objective: To determine the efficacy of intravenous vitamin C in reducing in-hospital mortality in moderate and severe cases of COVID-19. Design: Parallel,
Vijay Kumar, Divendu Bhushan, Sushmita Supriya, Avinash Aravind Ganapule, Pallavi Lohani, Shyama, Sanjay Pandey, Pramod Kumar Majhi, Utpal Anand, Ramesh Kumar, Umesh Kumar Bhadani   +10 more
doaj   +3 more sources

Intravenous Vitamin C for Cancer Therapy – Identifying the Current Gaps in Our Knowledge

Frontiers in Physiology, 2018
The use of intravenous vitamin C (IVC) for cancer therapy has long been an area of intense controversy. Despite this, high dose IVC has been administered for decades by complementary health care practitioners and physicians, with little evidence base ...
Anitra C. Carr, John Cook
doaj   +4 more sources

The Use of Intravenous Vitamin C as a Supportive Therapy for a Patient with Glioblastoma Multiforme [PDF]

Antioxidants, 2018
Glioblastoma multiforme is a high grade malignant brain tumour with a poor prognosis. Here we report the case of a woman with glioblastoma who lived for over four years from diagnosis (median survival 12 months and 2% survival for three years ...
Nicola Baillie, Anitra C. Carr, Selene Peng   +2 more
doaj   +5 more sources