Results 1 to 10 of about 59,789 (242)

Low Vitamin C Concentrations in Patients with Community-Acquired Pneumonia Resolved with Pragmatic Administration of Intravenous and Oral Vitamin C

Antioxidants, 2023
Community-acquired pneumonia (CAP) is characterized by elevated markers of inflammation and oxidative stress and depleted circulating concentrations of the antioxidant nutrient vitamin C.
Anitra C. Carr, Emma Vlasiuk, Masuma Zawari, Amy Scott-Thomas, Malina Storer, Michael Maze, Stephen T. Chambers   +6 more
doaj   +5 more sources

The effectiveness of high-dose intravenous vitamin C for patients with coronavirus disease 2019: A systematic review and meta-analysis [PDF]

Complementary Therapies in Medicine, 2022
Objectives: Vitamin C has anti-inflammatory effects. This review aimed to investigate the therapeutic effect of high-dose intravenous vitamin C (HDIVC) in patients with coronavirus disease 2019 (COVID-19). Methods: The following key phrases were searched
Sang Gyu Kwak, Yoo Jin Choo, Min Cheol Chang   +2 more
doaj   +4 more sources

The Use of Intravenous Vitamin C as a Supportive Therapy for a Patient with Glioblastoma Multiforme [PDF]

Antioxidants, 2018
Glioblastoma multiforme is a high grade malignant brain tumour with a poor prognosis. Here we report the case of a woman with glioblastoma who lived for over four years from diagnosis (median survival 12 months and 2% survival for three years ...
Nicola Baillie, Anitra C. Carr, Selene Peng   +2 more
doaj   +5 more sources

Intravenous vitamin C administration to patients with septic shock: a pilot randomised controlled trial [PDF]

Critical Care, 2022
Background Intravenous vitamin C administration in septic shock may have a sparing effect on vasopressor requirements, and vitamin C’s enzyme cofactor functions provide a mechanistic rationale.
Patrice Rosengrave, Emma Spencer, Jonathan Williman, Jan Mehrtens, Stacey Morgan, Tara Doyle, Kymbalee Van Der Heyden, Anna Morris, Geoff Shaw, Anitra C. Carr   +9 more
doaj   +2 more sources

Pharmacokinetic Evaluation of Intravenous Vitamin C: A Classic Pharmacokinetic Study. [PDF]

Clin Pharmacokinet, 2022
Intravenous vitamin C (IVC) is used in a variety of disorders with limited supporting pharmacokinetic data. Herein we report a pharmacokinetic study in healthy volunteers and cancer participants with IVC doses in the range of 1-100 g.A pharmacokinetic study was conducted in 21 healthy volunteers and 12 oncology participants.
Chen P, Reed G, Jiang J, Wang Y, Sunega J, Dong R, Ma Y, Esparham A, Ferrell R, Levine M, Drisko J, Chen Q.   +11 more
europepmc   +3 more sources

Intravenous Vitamin C and Cancer [PDF]

Integrative Cancer Therapies, 2014
Background. Intravenous vitamin C (IVC) is a contentious adjunctive cancer therapy, widely used in naturopathic and integrative oncology settings. We conducted a systematic review of human interventional and observational studies assessing IVC for use in cancer patients. Methods.
Heidi Fritz, Kieran Cooley, Jessie Mcgowan   +2 more
exaly   +3 more sources

Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials. [PDF]

JAMA, 2023
ImportanceThe efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain.ObjectiveTo determine whether vitamin C improves outcomes for patients with COVID-19.Design, Setting, and ParticipantsTwo prospectively harmonized randomized clinical trials enrolled critically ill patients receiving organ support in intensive care units (90 sites)
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Horvat C, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F.   +85 more
europepmc   +6 more sources

Effect of perioperative single dose intravenous vitamin C on pain after total hip arthroplasty [PDF]

Journal of Orthopaedic Surgery and Research
Introduction Vitamin c can relieve the pain after other diseases, but there are no studies on whether vitamin C can relieve the pain after hip replacement.
Guangtao Han, Yanfeng Gan, Qin Wang, Shuo Sun, Pengde Kang   +4 more
doaj   +2 more sources

Is intravenous vitamin C contraindicated in patients with G6PD deficiency? [PDF]

Critical Care, 2019
Paul E. Marik
doaj   +5 more sources

Case report: The efficacy of adding high doses of intravenous vitamin C to the combination therapy of atezolizumab and bevacizumab in unresectable HCC [PDF]

Frontiers in Medicine
IntroductionVitamin C (L-ascorbic acid) plays a vital role in human physiology, serving as both an antioxidant and a cofactor in enzymatic reactions. High-dose intravenous Vitamin C can achieve significantly elevated plasma concentrations, potentially ...
Waleed Kian, Waleed Kian, Waleed Kian, Areen A. Remilah, Celine Shatat, Maria Spector, Laila C. Roisman, Larisa Ryvo   +7 more
doaj   +2 more sources