Results 41 to 50 of about 3,438 (125)

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Bridging the diagnostic and therapeutic gaps in retinoblastoma: A referral center’s perspective from Southeast Asia

AJO International
Purpose: To highlight diagnostic and therapeutic disparities in retinoblastoma care and share our institutional approach to bridging these gaps in a resource-limited setting in Southeast Asia. Design: Perspective and selected literature review.
Thanaporn Kritfuangfoo, Duangnate Rojanaporn   +1 more
doaj   +1 more source

Response‐adapted consolidation and salvage strategies in secondary central nervous system lymphoma: Insights from a multicentre cohort

British Journal of Haematology, Volume 209, Issue 2, Page 524-533, August 2026.
Summary Secondary central nervous system lymphoma (SCNSL) remains a rare but challenging manifestation of aggressive lymphomas, with limited prospective data to guide treatment decisions in the modern therapeutic era. We conducted a multicentre retrospective cohort study of 105 consecutively treated adult patients diagnosed with SCNSL between 2016 and ...
Farina Eigendorff, Fabian Görke, Vanja Zeremski, Sophia Wollnitza, Evgenii Shumilov, Georg Lenz, Ellen Obstfelder, Inken Hilgendorf, Vladan Vučinić, Andreas Hochhaus, Ulf Schnetzke   +10 more
wiley   +1 more source

A rare presentation of bilateral ophthalmic relapse of pediatric chronic myeloid leukemia: Multimodal imaging and treatment

Oman Journal of Ophthalmology, 2023
Chronic myeloid leukemia (CML) rarely presents under 15 years of age, and its incidence is as low as 2% of all leukemia. Ophthalmic manifestations often present either initially with the diagnosis or as a sign of relapse after remission.
Gaurav Garg, Narendra Patidar, Satyendra Dubey   +2 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Creation of a Retinoblastoma Registry in a Resource‐Limited Country in Sub‐Saharan Africa

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Retinoblastoma (RB) is the most common ocular tumor in young children, originating from the developing retina, with the burden remaining higher in regions of low socio‐demographic index. A registry of RB is essential for creating effective referral networks for evaluating treatment patterns and contributing to the global pool of ...
Benjamin Abaidoo, Vera Adobea Essuman, Helen Dimaras, Kwesi Nyan Amissah‐Arthur, Vera Mawusime Beyuo, Doreen Amankwaa‐Frempong, Peter Forson Ackah, Andrea Nimako, Dziffa‐Bella Imelda‐Odille Ofori‐Adjei, Naa Naamuah Tagoe, Lauretta Pinamang Owusu‐Asare, Yaw Akye Essuman, Isabella Perpetual Arthur, Gloria Gyamaa Kyeremeh, Louis Oteng‐Gyimah, Gilbert Batieka Bonsaana, Judith Simon, Benedicta Appiah‐Thompson, James Fiifi Addy, Adolf Ollennu, Lorna Awo Renner, Chris Guure, Vivian Paintsil, Sally Peprah   +23 more
wiley   +1 more source

Ocular Survival Following Intravitreal Melphalan as Adjuvant Treatment for Vitreous Retinoblastoma Seeding

Clinical Ophthalmology, 2023
Ghaida Alahmadi,1 Azza MY Maktabi,2 Gorka Sesma,1 Saleh Almesfer1 1Pediatric Ophthalmology and Strabismus Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Pathology and Laboratory Medicine Department, King Khaled Eye Specialist ...
Alahmadi G, Maktabi AMY, Sesma G, Almesfer S   +3 more
doaj  

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Vascular tumors of the choroid and retina

Indian Journal of Ophthalmology, 2015
Vascular tumors of the retina and choroid can be seen occasionally. In the following article, the key clinical and diagnostic features of the major retinal and choroidal vascular tumors, their systemic associations, and the literature pertaining to the ...
P Mahesh Shanmugam, Rajesh Ramanjulu
doaj   +1 more source