Results 61 to 70 of about 8,508 (214)

Intravitreal Therapy for Diabetic Macular Edema: An Update

open access: yesJournal of Ophthalmology, 2021
Diabetic macular edema (DME) represents a prevalent and disabling eye condition. Despite that DME represents a sight-threatening condition, it is also among the most accessible to treatment.
Claudio Furino   +3 more
doaj   +1 more source

Uso do voriconazol oral como tratamento adjuvante da infecção fúngica grave da córnea: relato de caso [PDF]

open access: yes, 2006
A case of Aspergillus flavus keratitis was successfully treated with oral voriconazole and penetrating keratoplasty after conventional antifungal medical therapy failure.O presente trabalho descreve o emprego do voriconazol sistêmico como adjuvante no ...
Freda, Roberto
core   +2 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

Low-dose melittin is safe for intravitreal administration and ameliorates inflammation in an experimental model of uveitis

open access: yesCurrent Research in Pharmacology and Drug Discovery, 2022
Uveitis is a group of sight-threatening ocular inflammatory disorders, whose mainstay of therapy is associated with severe adverse events, prompting the investigation of alternative treatments.
Brenda Fernanda Moreira Castro   +9 more
doaj   +1 more source

Intravitreous Delivery of the Corticosteroid Fluocinolone Acetonide Attenuates Retinal Degeneration in S334ter-4 Rats [PDF]

open access: yesInvestigative Opthalmology & Visual Science, 2010
To study the neuroprotective properties of low-dose, sustained-release intravitreous fluocinolone acetonide (FA) in transgenic S334ter-4 rats.S334ter-4 rats aged 4 weeks were divided into four groups: 0.5 microg/d FA-loaded intravitreous drug delivery implant (IDDI); 0.2 microg/d FA-loaded IDDI; inactive IDDI; and unoperated controls ...
Inna V, Glybina   +4 more
openaire   +2 more sources

The impact of systemic long‐term medications for the development of age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä   +3 more
wiley   +1 more source

The impact of intravitreal therapy of diabetic macular edema on the local and systemic production of cytokines

open access: yesРоссийский офтальмологический журнал, 2023
Purpose: to analyze the levels of cytokines in intraocular fluid (IF) and blood plasma of patients with diabetic macular edema (DME) previously untreated by intravitreal therapy before and after the therapy by angiogenesis inhibitor or a corticosteroid ...
A. Zh. Fursova   +4 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

open access: yesActa Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco   +2 more
wiley   +1 more source

Intravitreal Corticosteroids in the Management of Refractory Macular Edema in Birdshot Chorioretinopathy

open access: yesInternational Medical Case Reports Journal
Birdshot chorioretinopathy (BCR) is a chronic, bilateral posterior uveitis characterized by yellow-white fundus lesions and a strong association with HLA-A29. Visual decline, often due to cystoid macular edema (CME) and retinal atrophy, necessitates early immunomodulatory therapy. This case report describes the clinical course of BCR and highlights the
João Alves Ambrósio   +5 more
openaire   +5 more sources

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider   +7 more
wiley   +1 more source

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