Results 81 to 90 of about 8,508 (214)

Aptamer‐Functionalized Nanocarriers for Bone and Joint Diseases: Engineering Design Rules and Translational Roadmap

Small Science, Volume 6, Issue 5, May 2026.
Aptamer‐functionalized nanocarriers represent a versatile platform for targeted therapy in bone and joint diseases. This review presents five complementary design strategies: free aptamers for soluble targets, bispecific multivalent constructs for enhanced avidity, nanoparticle‐conjugated aptamers for selective tissue accumulation, aptamer‐based ...
Hamdi Al‐Azzani, Djandan Tadum Arthur Vithran, Syeda Sundas Batool, Malek Mohammed Ali Alshabi, Wenhu Zhou, Xiaoqiang Mao   +5 more
wiley   +1 more source

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

Treatment of Punctate Inner Choroidopathy with Choroidal Neovascularization Using Corticosteroid and Intravitreal Ranibizumab

BioMed Research International, 2018
Background. To evaluate the treatment outcomes of patients with punctate inner choroidopathy (PIC) and secondary choroidal neovascularization (CNV). Methods. This is a retrospective study of 24 eyes in 22 patients suffering from PIC with CNV. Patients were treated with intravitreal ranibizumab monotherapy (14 eyes) or combined oral corticosteroid and ...
Wei Wu, Shiying Li, Haiwei Xu, Yong Liu, Yi Wang, Timothy Y. Y. Lai, Zheng Qin Yin   +6 more
openaire   +2 more sources

Real‐world outcomes of aflibercept 8 mg in patients previously treated for neovascular age‐related macular degeneration

Acta Ophthalmologica, Volume 104, Issue 3, Page 296-304, May 2026.
Abstract Purpose To evaluate visual, anatomical and safety outcomes of aflibercept 8 mg in previously treated patients with neovascular age‐related macular degeneration (nAMD). Methods This retrospective study included nAMD patients switched to aflibercept 8 mg from prior anti‐VEGF therapies at Sahlgrenska University Hospital between February 2024 and ...
Imadeddin Abu Ishkheidem, Esra Inci, Martin Breimer, Sofia Töyrä Silfverswärd, Madeleine Zetterberg, Marita Andersson Grönlund   +5 more
wiley   +1 more source

Efficacy and safety of different doses of a slow-release corticosteroid implant for macular edema: meta-analysis of randomized controlled trials

Drug Design, Development and Therapy, 2015
Qingyu Liu,1,2,* Mengmei He,1,2,* Hui Shi,1,3 Qianyi Wang,1,2 Yaru Du,1,3 Junling Liu,1,2 Chengda Ren,1,2 Ding Xu,1 Jing Yu1 1Department of Ophthalmology, Shanghai Tenth People’s Hospital, Shanghai, 2Tongji University School of Medicine, Shanghai,
Liu QY, He MM, Shi H, Wang QY, Du YR, Liu JL, Ren CD, Xu D, Yu J   +8 more
doaj  

Clinical and functional evaluation of efficiency in the treatment of macular edema associated with thrombosis of the central retinal vein and its branches

Офтальмохирургия, 2019
Purpose. An assessment of the efficacy of a prolonged corticosteroid and anti-VEGF therapy in the treatment of macular edema with thrombosis of the central retinal vein and its branches.Material and methods.
T. G. Kamenskikh, Y. S. Batishcheva, E. V. Gileva, I. O. Kolbenev   +3 more
doaj   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, Volume 104, Issue 3, Page e300-e311, May 2026.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Corticosteroid induced glaucoma

JKS (Jurnal Kedokteran Syiah Kuala), 2009
ABSTR4.K.  Corticosteroid induced glaucoma adalah glaukorna yang  disebabkan   oleh pemakaian terapi kortikosteroid   jangka  panjang  baik secara   oral, intravena,   topikal,  periokular, ataupun  intravitreal.
Lia Meuthia Zaini
doaj  

Persistent Diabetic Macular Edema: A Comprehensive Review of Current Treatments and Emerging Therapeutic Options

Journal of Current Ophthalmology
Purpose: To comprehensively review and evaluate the therapeutic strategies for persistent diabetic macular edema (DME), with a particular emphasis on established treatments.
Shahin Faghihi, Hooshang Faghihi, Mir Alborz Faiez, Abbas Mohammadi, Esmaeil Asadi Khameneh, Elias Khalili Pour, Hamid Riazi-Esfahani   +6 more
doaj   +1 more source

Multifocal Central Serous Chorioretinopathy Associated with Steroids in a Patient with Myasthenia Gravis

Case Reports in Ophthalmology, 2013
We present a case of bilateral multifocal central serous chorioretinopathy in a 40-year-old male who suffered from myasthenia gravis and was receiving oral prednisolone.
Maria Stefaniotou, Eleni Vourda, Andreas Katsanos, Miltiadis Aspiotis   +3 more
doaj   +1 more source