Results 141 to 150 of about 1,540,879 (346)
Intravitreal Injection of Splice-switching Oligonucleotides to Manipulate Splicing in Retinal Cells
Molecular Therapy: Nucleic Acids, 2015 Leber congenital amaurosis is a severe hereditary retinal dystrophy responsible for neonatal blindness. The most common disease-causing mutation (c.2991+1655A>G; 10–15%) creates a strong splice donor site that leads to insertion of a cryptic exon ...
X. Gérard +4 more
semanticscholar +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Artificial intelligence (AI) has comparable accuracy to ophthalmologists for diabetic retinopathy (DR) screening, yet its cost‐effectiveness is crucial for implementation. Our review of 18 health economic analyses of AI versus manual grading for DR found significant methodological variation, with cost‐utility analysis and Markov modelling ...
James Leigh +3 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2021 BACKGROUND AND OBJECTIVE: Acute endophthalmitis is one of the most dangerous complications after eye surgeries. Knowing the severity of this complication is critical for treatment policy in ophthalmology departments.
A Eftekhari Milani +4 more
doaj
Sterile Inflammation after Intravitreal Injection of Aflibercept in a Korean Population
Korean Journal of Ophthalmology, 2015 Purpose To report the frequency and clinical features of sterile inflammation after intravitreal aflibercept injection in a Korean population. Methods A single-center, retrospective study was performed in patients who received intravitreal aflibercept ...
J. Kim, Y. You, O. Kwon, S. Kim
semanticscholar +1 more source
Cell Proliferation, EarlyView.In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma +20 more
wiley +1 more source
Intravitreal bevacizumab versus ranibizumab: Effects on the vessels of the fellow non-treated eye
Journal of Current Ophthalmology, 2019 Purpose: To evaluate the effects of anti-vascular endothelial growth factors (anti-VEGF) on the vessels of the non-treated eyes following intravitreal injections.
Mohammadreza Peyman +4 more
doaj +1 more source
Journal of Diabetes Investigation, EarlyView.Under physiological conditions, deformable erythrocytes pass smoothly through the capillary network, maintaining retinal capillary perfusion (A). In pathological conditions, reduced erythrocyte deformability causes irregular passage and stagnation within capillaries, resulting in localized blood flow stasis and microvascular congestion, leading to ...
Ye Eun Han +5 more
wiley +1 more source
The adenylate cyclase receptor complex and aqueous humor formation. [PDF]
, 1984 The secretory tissue of the eye, the ciliary processes, contains an enzyme receptor complex, composed of membrane proteins, the catalytic moiety of the enzyme adenylate cyclase, a guanyl nucleotide regulatory protein (or N protein), and other features ...
Caprioli, J, Sears, M
core +1 more source
Veterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth +3 more
wiley +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
, 2011 Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H. +2 more
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